Inhibitory Effect of Chlorpromazine on Arterial Lipid Deposition in Cholesterol Fed Rabbits.

Summary The blood cholesterol levels of cholesterol-fed rabbits given daily intramuscular injections of chlorpromazine fail to rise as high as in rabbits fed cholesterol only. Deposition of lipid in arteries and in the liver is also greatly reduced. Repeated injections of chlorpromazine in rabbits o...

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Veröffentlicht in:Experimental biology and medicine (Maywood, N.J.) N.J.), 1956-10, Vol.93 (1), p.121-124
Hauptverfasser: Wilens, Sigmund L., McCluskey, Robert T., Somoza, Cësar
Format: Artikel
Sprache:eng
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Zusammenfassung:Summary The blood cholesterol levels of cholesterol-fed rabbits given daily intramuscular injections of chlorpromazine fail to rise as high as in rabbits fed cholesterol only. Deposition of lipid in arteries and in the liver is also greatly reduced. Repeated injections of chlorpromazine in rabbits on stock diets may cause transient periods of mild hypercholesterolemia.
ISSN:0037-9727
1535-3702
1535-3699
DOI:10.3181/00379727-93-22683