Improved Cope-type hydroamination reactivity of hydrazine derivatives

A systematic investigation on the metal-free, Cope-type hydroamination reactivity of hydrazides and analogues is reported. Optimization of the hydrazide structure resulted in more facile intramolecular reactivity and enabled intermolecular reactions of alkenes, thus providing a direct approach to po...

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Veröffentlicht in:	Chemical communications (Cambridge, England) England), 2011-01, Vol.47 (1), p.562-564
Hauptverfasser:	Loiseau, Francis, Clavette, Christian, Raymond, Michaël, Roveda, Jean-Grégoire, Burrell, Alishya, Beauchemin, André M
Format:	Artikel
Sprache:	eng
Schlagworte:	Amination Hydrazines - chemical synthesis Hydrazines - chemistry Molecular Structure Stereoisomerism
Online-Zugang:	Volltext
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Beschreibung
Zusammenfassung:	A systematic investigation on the metal-free, Cope-type hydroamination reactivity of hydrazides and analogues is reported. Optimization of the hydrazide structure resulted in more facile intramolecular reactivity and enabled intermolecular reactions of alkenes, thus providing a direct approach to polysubstituted hydrazides.
ISSN:	1359-7345 1364-548X
DOI:	10.1039/c0cc02403a