Histamine Sensitivity of Adrenalectomized and Pertussis-Treated Mice

Histamine Sensitivity of Adrenalectomized and Pertussis-Treated Mice

Summary In a Swiss-Kebster strain of mice. Pertussis vaccine treatment increased the sensitivity to intravenously injected histamine 33 times. Whereas surgical adrenalectomy had no significant effect on sensitivity to histamine. This finding. in addition to lack of direct evidence to the contrary. w...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Experimental biology and medicine (Maywood, N.J.) N.J.), 1955-12, Vol.90 (3), p.726-728
Hauptverfasser: Gauthier, Geraldine F., Loew, E.R., Jenkins, H.J.
Format: Artikel
Sprache:eng
Schlagworte:
Adrenal Glands - surgery
Animals
Histamine
Histamine Agents
Mice
Old Medline
Vaccination
Vaccines
Whooping Cough
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:Summary In a Swiss-Kebster strain of mice. Pertussis vaccine treatment increased the sensitivity to intravenously injected histamine 33 times. Whereas surgical adrenalectomy had no significant effect on sensitivity to histamine. This finding. in addition to lack of direct evidence to the contrary. warrants the conclusion that Hemophillus pesrtussis vaccine enhances sensitivity of mice to histamine through some mechanism other than impairment of adrenal function.
ISSN:0037-9727
1535-3702
1535-3699
DOI:10.3181/00379727-90-22150