Inactivation of Horizontal Cells in Turtle Retina by Glutamate and Aspartate

Glutamate and aspartate completely suppress the activity of horizontal cells but only partially affect the response of receptor cells to light. The changes observed in the receptor responses are consistent with the interruption of a synaptically mediated process rather than with a direct action on t...

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Veröffentlicht in:Science (American Association for the Advancement of Science) 1972-11, Vol.178 (4062), p.767-768
Hauptverfasser: Cervetto, Luigi, MacNichol, Edward F.
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container_title Science (American Association for the Advancement of Science)
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creator Cervetto, Luigi
MacNichol, Edward F.
description Glutamate and aspartate completely suppress the activity of horizontal cells but only partially affect the response of receptor cells to light. The changes observed in the receptor responses are consistent with the interruption of a synaptically mediated process rather than with a direct action on the receptor membrane.
doi_str_mv 10.1126/science.178.4062.767
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source American Association for the Advancement of Science; Jstor Complete Legacy; MEDLINE
subjects Animals
Aspartic Acid - pharmacology
Cell membranes
Depolarization
Electroretinography
Glutamates - pharmacology
In Vitro Techniques
Luminous intensity
Membrane Potentials - drug effects
Perfusion
Photoreceptor Cells - physiology
Photoreceptors
Receptors
Retina
Retina - cytology
Retina - drug effects
Retina - physiology
Sodium
Turtles
title Inactivation of Horizontal Cells in Turtle Retina by Glutamate and Aspartate
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