Inactivation of Horizontal Cells in Turtle Retina by Glutamate and Aspartate

Glutamate and aspartate completely suppress the activity of horizontal cells but only partially affect the response of receptor cells to light. The changes observed in the receptor responses are consistent with the interruption of a synaptically mediated process rather than with a direct action on t...

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Veröffentlicht in:	Science (American Association for the Advancement of Science) 1972-11, Vol.178 (4062), p.767-768
Hauptverfasser:	Cervetto, Luigi, MacNichol, Edward F.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Aspartic Acid - pharmacology Cell membranes Depolarization Electroretinography Glutamates - pharmacology In Vitro Techniques Luminous intensity Membrane Potentials - drug effects Perfusion Photoreceptor Cells - physiology Photoreceptors Receptors Retina Retina - cytology Retina - drug effects Retina - physiology Sodium Turtles
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Beschreibung
Zusammenfassung:	Glutamate and aspartate completely suppress the activity of horizontal cells but only partially affect the response of receptor cells to light. The changes observed in the receptor responses are consistent with the interruption of a synaptically mediated process rather than with a direct action on the receptor membrane.
ISSN:	0036-8075 1095-9203
DOI:	10.1126/science.178.4062.767