Human Prolactin: 24-Hour Pattern with Increased Release during Sleep

Human Prolactin: 24-Hour Pattern with Increased Release during Sleep

Human prolactin was measured in plasma by radioimmunoassay at 20-minute intervals for a 24-hour period in each of six normal adults, whose sleep-wake cycles were monitored polygraphically. A marked diurnal variation in plasma concentrations was demonstrated, with highest values during sleep; periods...

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Veröffentlicht in:Science (American Association for the Advancement of Science) 1972-09, Vol.177 (4055), p.1205-1207
Hauptverfasser: Sassin, J. F., Frantz, A. G., Weitzman, E. D., Kapen, S.
Format: Artikel
Sprache:eng
Schlagworte:
Adult
Antibodies
Catheters
Circadian Rhythm
Eyes
Female
Fovea
Growth Hormone - blood
Growth hormones
Hormones
Human growth
Humans
Iodine Isotopes
Male
Prolactin - blood
Radioimmunoassay
Sex Factors
Sleep
Sleep stages
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Zusammenfassung:Human prolactin was measured in plasma by radioimmunoassay at 20-minute intervals for a 24-hour period in each of six normal adults, whose sleep-wake cycles were monitored polygraphically. A marked diurnal variation in plasma concentrations was demonstrated, with highest values during sleep; periods of episodic release occurred throughout the 24 hours.
ISSN:0036-8075
1095-9203
DOI:10.1126/science.177.4055.1205