Simian Sarcoma Virus, Type 1 (Lagothrix): Focus Assay and Demonstration of Nontransforming Associated Virus
The focal transformation of marmoset lung cells by simian sarcoma virus, type 1 (SSV-1) was quantitative without an agar overlay required. Pretreatment of the indicator cells with diethylaminoethyl-dextran increased the sensitivity 10–50 times. A 10-100 fold excess of nontransforming associated viru...
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| Veröffentlicht in: | JNCI : Journal of the National Cancer Institute 1972-06, Vol.48 (6), p.1905-1908 |
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| container_end_page | 1908 |
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| container_issue | 6 |
| container_start_page | 1905 |
| container_title | JNCI : Journal of the National Cancer Institute |
| container_volume | 48 |
| creator | Wolfe, Lauren G. Smith, Richard K. Deinhardt, Friedrich |
| description | The focal transformation of marmoset lung cells by simian sarcoma virus, type 1 (SSV-1) was quantitative without an agar overlay required. Pretreatment of the indicator cells with diethylaminoethyl-dextran increased the sensitivity 10–50 times. A 10-100 fold excess of nontransforming associated virus (SSAV-1) was demonstrated in SSV-1 stocks by interference tests and electron microscopy. SSV-1 produced by transformed marmoset, human, or cat cells retained its oncogenicity for marmosets. |
| doi_str_mv | 10.1093/jnci/48.6.1905 |
| format | Article |
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| fulltext | fulltext |
| identifier | ISSN: 0027-8874 |
| ispartof | JNCI : Journal of the National Cancer Institute, 1972-06, Vol.48 (6), p.1905-1908 |
| issn | 0027-8874 1460-2105 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_81574320 |
| source | MEDLINE; Oxford University Press Journals Digital Archive Legacy |
| subjects | Animals Biological Assay Cell Transformation, Neoplastic Dextrans Haplorhini Oncogenic Viruses Sarcoma, Experimental - etiology Satellite Viruses |
| title | Simian Sarcoma Virus, Type 1 (Lagothrix): Focus Assay and Demonstration of Nontransforming Associated Virus |
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