ACTH Release by in vitro Pituitary. Effect of Pitressin and Purified Arginine-Vasopressin.

Summary A modified tissue culture technic for rat pituitary was used for assaying the ACTH releasing activity of commercial Pitressin and purified vasopressin. Pitressin increased ACTH release whereas highly purified arginine-vasopressin had no effect. The ACTH hypophysotrope activity of commercial...

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Veröffentlicht in:	Experimental biology and medicine (Maywood, N.J.) N.J.), 1955-07, Vol.89 (3), p.365-366
Hauptverfasser:	Guillemin, Roger, Hearn, Walter R.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adrenocorticotropic Hormone - physiology Arginine - pharmacology Arginine Vasopressin In Vitro Techniques Old Medline Pituitary Diseases Pituitary Gland Vasopressins - pharmacology
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Zusammenfassung:	Summary A modified tissue culture technic for rat pituitary was used for assaying the ACTH releasing activity of commercial Pitressin and purified vasopressin. Pitressin increased ACTH release whereas highly purified arginine-vasopressin had no effect. The ACTH hypophysotrope activity of commercial Pitressin is attributed to a contaminant of vasopressin of probable hypothalamic origin.
ISSN:	0037-9727 1535-3702 1535-3699
DOI:	10.3181/00379727-89-21812