Influence of Calcium and Serum Albumin on Clearing of Lipemic Dog Plasma In vitro

Summary 1. Studies are reported on the effect of 3 different anticoagulant systems on the rate and degree of optical clearing of lip-emic plasma by heparin clearing factor plasma. 2. Calcium binding anticoagulants decreased lipemia clearing proportional to the binding. 3. Protein binding anticoagulants also retarded or abolished clearing. 4. Chy-lomicra suspended in normal plasma cleared at a faster rate than those suspended in physiological salt solution. The addition of Ca or albumin enhanced the rate of clearing in physiological salt solution and the addition of both Ca and albumin resulted in almost complete restoration of clearing activity.