Nuclear magnetic resonance spectrum of lysine-vasopressin in aqueous solution and its structural implictions

Nuclear magnetic resonance spectrum of lysine-vasopressin in aqueous solution and its structural implictions

The peaks in the proton NMR spectrum of lysine-vasopressin in aqueous solution at pH 3-5 were assigned to particular amino-acid residues by the use of the results of dilution studies and NH-C(alpha)H and C(alpha)H-C(beta)H decoupling experiments. The conformation of lysine-vasopressin in water diffe...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Proceedings of the National Academy of Sciences - PNAS 1972-08, Vol.69 (8), p.2169-2173
Hauptverfasser: Von Dreele, P H, Brewster, A I, Dadok, J, Scheraga, H A, Bovey, F A, Ferger, M F, Du Vigneaud, V
Format: Artikel
Sprache:eng
Schlagworte:
Deuterium
Dimethyl Sulfoxide
Hydrogen-Ion Concentration
Lysine
Magnetic Resonance Spectroscopy
Protein Conformation
Solutions
Structure-Activity Relationship
Vasopressins
Water
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:The peaks in the proton NMR spectrum of lysine-vasopressin in aqueous solution at pH 3-5 were assigned to particular amino-acid residues by the use of the results of dilution studies and NH-C(alpha)H and C(alpha)H-C(beta)H decoupling experiments. The conformation of lysine-vasopressin in water differs from its conformation in dimethylsulfoxide.
ISSN:0027-8424
DOI:10.1073/pnas.69.8.2169