Separation of Skin Reactive Intestinal Cancer Antigen from the Carcinoembryonic Antigen of Gold

Soluble fractions of human intestinal cancer and fetal intestinal cell membranes produced delayed hypersensitivity reactions in patients with intestinal cancer. These soluble fractions and perchloric acid extracts of intestinal cancer cells were fractionated by polacrylamide-gel electrophoresis. The...

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Veröffentlicht in:	Science (American Association for the Advancement of Science) 1972-09, Vol.177 (4052), p.887-889
Hauptverfasser:	Hollinshead, Ariel C., McWright, C. Glen, Alford, T. Crandall, Glew, Donald H., Gold, Phil, Herberman, Ronald B.
Format:	Artikel
Sprache:	eng
Schlagworte:	Antigens Antigens - isolation & purification Antigens, Neoplasm - isolation & purification Cell membranes Colonic Neoplasms - immunology Coloring Agents Diabetes Electrophoresis Fetus - immunology Gels Humans Hypersensitivity, Delayed Insulin Intestinal neoplasms Intestines - immunology P branes Reactivity Rectal Neoplasms - immunology Skin Skin Tests
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Beschreibung
Zusammenfassung:	Soluble fractions of human intestinal cancer and fetal intestinal cell membranes produced delayed hypersensitivity reactions in patients with intestinal cancer. These soluble fractions and perchloric acid extracts of intestinal cancer cells were fractionated by polacrylamide-gel electrophoresis. The Gold carcinoembryonic antigen was found in a region of the gels different from that of the skin reactive antigen.
ISSN:	0036-8075 1095-9203
DOI:	10.1126/science.177.4052.887