Burkitt's lymphoma and malaria

An analysis of malarial parasitaemia, splenomegaly, antimalarial antibodies, immunoglobulin levels, and reticuloendothelial phagocytic function was undertaken in patients with Burkitt's lymphoma in Uganda. The results reveal no difference between the Burkitt patients and controls, with the exce...

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Veröffentlicht in:	Transactions of the Royal Society of Tropical Medicine and Hygiene 1972, Vol.66 (2), p.285-291
Hauptverfasser:	Ziegler, John L., Bluming, Avrum Z., Morrow, Richard H., Cohen, Martin H., Fife, Earl H., Finerty, John F., Woods, Roy
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Antibodies Blood - microbiology Burkitt Lymphoma - etiology Burkitt Lymphoma - immunology Burkitt Lymphoma - microbiology Burkitt Lymphoma - physiopathology Child Child, Preschool Chronic Disease Complement Fixation Tests Fluorescent Antibody Technique Humans Immunodiffusion Immunoglobulins - analysis Malaria - complications Malaria - immunology Mononuclear Phagocyte System - physiopathology Phagocytosis Plasmodium falciparum - immunology Plasmodium malariae - immunology Splenomegaly - complications
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Beschreibung
Zusammenfassung:	An analysis of malarial parasitaemia, splenomegaly, antimalarial antibodies, immunoglobulin levels, and reticuloendothelial phagocytic function was undertaken in patients with Burkitt's lymphoma in Uganda. The results reveal no difference between the Burkitt patients and controls, with the exception of lower IgM levels among the lymphoma patients. This study provides partial support for the epidemiological evidence incriminating malaria as a co-factor in the aetiology of Burkitt's lymphoma.
ISSN:	0035-9203 1878-3503
DOI:	10.1016/0035-9203(72)90159-9