Primary Lymphoma of the Vagina

Lymphoma of the female genital tract is seen more commonly as a secondary involvement, rarely as a primary lesion. The case described exemplifies a malignant lymphoma, reticulum cell sarcoma, presenting in the vagina as the initial manifestation. The patientʼs death was due to acute monocytic leukemia, the original involvement having been controlled by irradiation. Reticulum cell sarcoma is radiosensitive and should be treated with adequate radiation therapy if the disease is not widespread. The overall 5-year survival for reticulum cell sarcoma is 15–20%. Approximately 7% of all cases of reticulum cell sarcoma will terminate as acute leukemia.