Prostaglandin E 1 and cardiac arrhythmia
Observations are presented of the influence of prostaglandin E 1 upon cardiac arrhythmia in dogs. Intravenous injection (0.5–4 μg·kg −1) or infusion (0.5–4 μg·kg −1·min −1) of prostaglandin E 1 effectively suppressed bigeminy occurring in the course of thialbarbitone anaesthesia. Ventricular tachyca...
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| Veröffentlicht in: | European journal of pharmacology 1972-05, Vol.18 (3), p.392-395 |
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| Hauptverfasser: | , , , |
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| container_end_page | 395 |
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| container_issue | 3 |
| container_start_page | 392 |
| container_title | European journal of pharmacology |
| container_volume | 18 |
| creator | Zijlstra, W.G. Brunsting, J.R. Ten Hoor, F. Vergroesen, A.J. |
| description | Observations are presented of the influence of prostaglandin E
1 upon cardiac arrhythmia in dogs. Intravenous injection (0.5–4 μg·kg
−1) or infusion (0.5–4 μg·kg
−1·min
−1) of prostaglandin E
1 effectively suppressed bigeminy occurring in the course of thialbarbitone anaesthesia. Ventricular tachycardia due to acute myocardial ischaemia was reversed to normal sinus rhythm by a single injection of 2 μg·kg
−1 PGE
1. |
| doi_str_mv | 10.1016/0014-2999(72)90041-6 |
| format | Article |
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1 upon cardiac arrhythmia in dogs. Intravenous injection (0.5–4 μg·kg
−1) or infusion (0.5–4 μg·kg
−1·min
−1) of prostaglandin E
1 effectively suppressed bigeminy occurring in the course of thialbarbitone anaesthesia. Ventricular tachycardia due to acute myocardial ischaemia was reversed to normal sinus rhythm by a single injection of 2 μg·kg
−1 PGE
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1 upon cardiac arrhythmia in dogs. Intravenous injection (0.5–4 μg·kg
−1) or infusion (0.5–4 μg·kg
−1·min
−1) of prostaglandin E
1 effectively suppressed bigeminy occurring in the course of thialbarbitone anaesthesia. Ventricular tachycardia due to acute myocardial ischaemia was reversed to normal sinus rhythm by a single injection of 2 μg·kg
−1 PGE
1.</description><subject>Anesthesia</subject><subject>Animals</subject><subject>Arrhythmias, Cardiac - drug therapy</subject><subject>Arrhythmias, Cardiac - etiology</subject><subject>bigeminy Cardiac arrhythmia</subject><subject>Blood Pressure - drug effects</subject><subject>Coronary Vessels - physiology</subject><subject>Dogs</subject><subject>Electrocardiography</subject><subject>Heart Rate - drug effects</subject><subject>Ligation</subject><subject>Male</subject><subject>Prostaglandin E 1</subject><subject>Prostaglandins - pharmacology</subject><subject>Prostaglandins - therapeutic use</subject><subject>Ventricular tachycardia</subject><issn>0014-2999</issn><issn>1879-0712</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1972</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNo9kE1LAzEQhoMotVb_gcKepB5WJ8nm6yJIqR9Q0IOeQ5rM2ki3rclW6L931xZPM_A-DO88hFxSuKVA5R0ArUpmjBkrdmMAKlrKIzKkWpkSFGXHZPiPnJKznL8AQBgmBmQggAvJ5JCM39I6t-5z6VYhroppQYtuK7xLITpfuJQWu3bRRHdOTmq3zHhxmCPy8Th9nzyXs9enl8nDrEQKWpZUVqxWHATAPKgQqJF1ZQwPyLmuqTconOdO1yg0Mq-FmQusQYGuOsxVfESu93c3af29xdzaJmaPy64grrfZaloZJUQPXh3A7bzBYDcpNi7t7OG1Lr_f59i1_YmYbPYRVx5DTOhbG9bRUrC9Stt7sr0nq5j9U2kl_wVI3WI7</recordid><startdate>197205</startdate><enddate>197205</enddate><creator>Zijlstra, W.G.</creator><creator>Brunsting, J.R.</creator><creator>Ten Hoor, F.</creator><creator>Vergroesen, A.J.</creator><general>Elsevier B.V</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7X8</scope></search><sort><creationdate>197205</creationdate><title>Prostaglandin E 1 and cardiac arrhythmia</title><author>Zijlstra, W.G. ; Brunsting, J.R. ; Ten Hoor, F. ; Vergroesen, A.J.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-e1086-1642f730500bd7dd196f4993de338f1c9e5ac3a8fe58e2c859b5ef07084499a43</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1972</creationdate><topic>Anesthesia</topic><topic>Animals</topic><topic>Arrhythmias, Cardiac - drug therapy</topic><topic>Arrhythmias, Cardiac - etiology</topic><topic>bigeminy Cardiac arrhythmia</topic><topic>Blood Pressure - drug effects</topic><topic>Coronary Vessels - physiology</topic><topic>Dogs</topic><topic>Electrocardiography</topic><topic>Heart Rate - drug effects</topic><topic>Ligation</topic><topic>Male</topic><topic>Prostaglandin E 1</topic><topic>Prostaglandins - pharmacology</topic><topic>Prostaglandins - therapeutic use</topic><topic>Ventricular tachycardia</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Zijlstra, W.G.</creatorcontrib><creatorcontrib>Brunsting, J.R.</creatorcontrib><creatorcontrib>Ten Hoor, F.</creatorcontrib><creatorcontrib>Vergroesen, A.J.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>MEDLINE - Academic</collection><jtitle>European journal of pharmacology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Zijlstra, W.G.</au><au>Brunsting, J.R.</au><au>Ten Hoor, F.</au><au>Vergroesen, A.J.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Prostaglandin E 1 and cardiac arrhythmia</atitle><jtitle>European journal of pharmacology</jtitle><addtitle>Eur J Pharmacol</addtitle><date>1972-05</date><risdate>1972</risdate><volume>18</volume><issue>3</issue><spage>392</spage><epage>395</epage><pages>392-395</pages><issn>0014-2999</issn><eissn>1879-0712</eissn><abstract>Observations are presented of the influence of prostaglandin E
1 upon cardiac arrhythmia in dogs. Intravenous injection (0.5–4 μg·kg
−1) or infusion (0.5–4 μg·kg
−1·min
−1) of prostaglandin E
1 effectively suppressed bigeminy occurring in the course of thialbarbitone anaesthesia. Ventricular tachycardia due to acute myocardial ischaemia was reversed to normal sinus rhythm by a single injection of 2 μg·kg
−1 PGE
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| fulltext | fulltext |
| identifier | ISSN: 0014-2999 |
| ispartof | European journal of pharmacology, 1972-05, Vol.18 (3), p.392-395 |
| issn | 0014-2999 1879-0712 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_81497554 |
| source | MEDLINE; Elsevier ScienceDirect Journals |
| subjects | Anesthesia Animals Arrhythmias, Cardiac - drug therapy Arrhythmias, Cardiac - etiology bigeminy Cardiac arrhythmia Blood Pressure - drug effects Coronary Vessels - physiology Dogs Electrocardiography Heart Rate - drug effects Ligation Male Prostaglandin E 1 Prostaglandins - pharmacology Prostaglandins - therapeutic use Ventricular tachycardia |
| title | Prostaglandin E 1 and cardiac arrhythmia |
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