Mass Spectrometric Behavior of Cardiac Steroid Aglycones of the Cardenolide Type

The mass spectra of several cardenolide aglycones are discussed, and the principal modes of fragmentation are outlined. In addition to conventional expulsions of functional groups, the spectra exhibit C15, C16, and C17 fragment ions, resulting by elimination of ring D and the side chain as well as i...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Journal of pharmaceutical sciences 1972-05, Vol.61 (5), p.765-769
Hauptverfasser:	Fayez, M.B.E., Negm, S.A.R.
Format:	Artikel
Sprache:	eng
Schlagworte:	Cardanolides cardenolides Cardenolides-analysis Cardenolides—analysis, mass spectroscopy Cardiac steroid aglycones Cardiac steroid aglycones, cardenolides—analysis, mass spectroscopy Chemical Phenomena Chemistry Mass Spectrometry mass spectroscopy Mass spectroscopy-analysis Mass spectroscopy—analysis, cardenolides Structure-Activity Relationship
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

container_end_page	769
container_issue	5
container_start_page	765
container_title	Journal of pharmaceutical sciences
container_volume	61
creator	Fayez, M.B.E. Negm, S.A.R.
description	The mass spectra of several cardenolide aglycones are discussed, and the principal modes of fragmentation are outlined. In addition to conventional expulsions of functional groups, the spectra exhibit C15, C16, and C17 fragment ions, resulting by elimination of ring D and the side chain as well as ions comprising the latter group with remnants of ring D.
doi_str_mv	10.1002/jps.2600610519
format	Article
fullrecord	<record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_81486593</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>S0022354915384586</els_id><sourcerecordid>81486593</sourcerecordid><originalsourceid>FETCH-LOGICAL-c4279-67143b4f44f33181c14489f668cd7d7670d938250b7bf3a3d4da708217674623</originalsourceid><addsrcrecordid>eNqFkUtPGzEUhS1UBCnttrtKs-puUnv8nCUNJbTi1SYSS8ux74BhEk_tCSX_voaJQCwqVl6c7xzJ30XoE8FjgnH19bZL40pgLAjmpN5BI8IrXApM5Ds0ykBVUs7qffQ-pVucMcz5HtrjmHKpxAhdnpmUilkHto9hCX30tvgGN-beh1iEppiY6LyxxayHGLwrDq_bjQ0rSI9hfwNPAKxC6x0U800HH9BuY9oEH7fvAZoff59PTsrTi-mPyeFpaVkl61JIwuiCNYw1lBJFLGFM1Y0QyjrppJDY1VRVHC_koqGGOuaMxKoiOWKiogfoyzDbxfBnDanXS58stK1ZQVgnrQhTgtc0g-MBtDGkFKHRXfRLEzeaYP1oUGeD-sVgLnzeLq8XS3DP-FZZzush_-tb2Lyxpn9ezl5tl0PXpx4enrsm3mkhqeT66nyqf7Hfx0dqSvVZ5tXAQzZ57yHqZD2sLDgf88W0C_5_3_gH6o-cxA</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>81486593</pqid></control><display><type>article</type><title>Mass Spectrometric Behavior of Cardiac Steroid Aglycones of the Cardenolide Type</title><source>MEDLINE</source><source>Wiley Online Library Journals Frontfile Complete</source><source>Alma/SFX Local Collection</source><creator>Fayez, M.B.E. ; Negm, S.A.R.</creator><creatorcontrib>Fayez, M.B.E. ; Negm, S.A.R.</creatorcontrib><description>The mass spectra of several cardenolide aglycones are discussed, and the principal modes of fragmentation are outlined. In addition to conventional expulsions of functional groups, the spectra exhibit C15, C16, and C17 fragment ions, resulting by elimination of ring D and the side chain as well as ions comprising the latter group with remnants of ring D.</description><identifier>ISSN: 0022-3549</identifier><identifier>EISSN: 1520-6017</identifier><identifier>DOI: 10.1002/jps.2600610519</identifier><identifier>PMID: 5035786</identifier><language>eng</language><publisher>Washington: Elsevier Inc</publisher><subject>Cardanolides ; cardenolides ; Cardenolides-analysis ; Cardenolides—analysis, mass spectroscopy ; Cardiac steroid aglycones ; Cardiac steroid aglycones, cardenolides—analysis, mass spectroscopy ; Chemical Phenomena ; Chemistry ; Mass Spectrometry ; mass spectroscopy ; Mass spectroscopy-analysis ; Mass spectroscopy—analysis, cardenolides ; Structure-Activity Relationship</subject><ispartof>Journal of pharmaceutical sciences, 1972-05, Vol.61 (5), p.765-769</ispartof><rights>1972 Wiley‐Liss, Inc., A Wiley Company</rights><rights>Copyright © 1972 Wiley‐Liss, Inc., A Wiley Company</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c4279-67143b4f44f33181c14489f668cd7d7670d938250b7bf3a3d4da708217674623</citedby><cites>FETCH-LOGICAL-c4279-67143b4f44f33181c14489f668cd7d7670d938250b7bf3a3d4da708217674623</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1002%2Fjps.2600610519$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1002%2Fjps.2600610519$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,778,782,1414,27907,27908,45557,45558</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/5035786$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Fayez, M.B.E.</creatorcontrib><creatorcontrib>Negm, S.A.R.</creatorcontrib><title>Mass Spectrometric Behavior of Cardiac Steroid Aglycones of the Cardenolide Type</title><title>Journal of pharmaceutical sciences</title><addtitle>J. Pharm. Sci</addtitle><description>The mass spectra of several cardenolide aglycones are discussed, and the principal modes of fragmentation are outlined. In addition to conventional expulsions of functional groups, the spectra exhibit C15, C16, and C17 fragment ions, resulting by elimination of ring D and the side chain as well as ions comprising the latter group with remnants of ring D.</description><subject>Cardanolides</subject><subject>cardenolides</subject><subject>Cardenolides-analysis</subject><subject>Cardenolides—analysis, mass spectroscopy</subject><subject>Cardiac steroid aglycones</subject><subject>Cardiac steroid aglycones, cardenolides—analysis, mass spectroscopy</subject><subject>Chemical Phenomena</subject><subject>Chemistry</subject><subject>Mass Spectrometry</subject><subject>mass spectroscopy</subject><subject>Mass spectroscopy-analysis</subject><subject>Mass spectroscopy—analysis, cardenolides</subject><subject>Structure-Activity Relationship</subject><issn>0022-3549</issn><issn>1520-6017</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1972</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkUtPGzEUhS1UBCnttrtKs-puUnv8nCUNJbTi1SYSS8ux74BhEk_tCSX_voaJQCwqVl6c7xzJ30XoE8FjgnH19bZL40pgLAjmpN5BI8IrXApM5Ds0ykBVUs7qffQ-pVucMcz5HtrjmHKpxAhdnpmUilkHto9hCX30tvgGN-beh1iEppiY6LyxxayHGLwrDq_bjQ0rSI9hfwNPAKxC6x0U800HH9BuY9oEH7fvAZoff59PTsrTi-mPyeFpaVkl61JIwuiCNYw1lBJFLGFM1Y0QyjrppJDY1VRVHC_koqGGOuaMxKoiOWKiogfoyzDbxfBnDanXS58stK1ZQVgnrQhTgtc0g-MBtDGkFKHRXfRLEzeaYP1oUGeD-sVgLnzeLq8XS3DP-FZZzush_-tb2Lyxpn9ezl5tl0PXpx4enrsm3mkhqeT66nyqf7Hfx0dqSvVZ5tXAQzZ57yHqZD2sLDgf88W0C_5_3_gH6o-cxA</recordid><startdate>197205</startdate><enddate>197205</enddate><creator>Fayez, M.B.E.</creator><creator>Negm, S.A.R.</creator><general>Elsevier Inc</general><general>Wiley Subscription Services, Inc., A Wiley Company</general><scope>BSCLL</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>197205</creationdate><title>Mass Spectrometric Behavior of Cardiac Steroid Aglycones of the Cardenolide Type</title><author>Fayez, M.B.E. ; Negm, S.A.R.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4279-67143b4f44f33181c14489f668cd7d7670d938250b7bf3a3d4da708217674623</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1972</creationdate><topic>Cardanolides</topic><topic>cardenolides</topic><topic>Cardenolides-analysis</topic><topic>Cardenolides—analysis, mass spectroscopy</topic><topic>Cardiac steroid aglycones</topic><topic>Cardiac steroid aglycones, cardenolides—analysis, mass spectroscopy</topic><topic>Chemical Phenomena</topic><topic>Chemistry</topic><topic>Mass Spectrometry</topic><topic>mass spectroscopy</topic><topic>Mass spectroscopy-analysis</topic><topic>Mass spectroscopy—analysis, cardenolides</topic><topic>Structure-Activity Relationship</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Fayez, M.B.E.</creatorcontrib><creatorcontrib>Negm, S.A.R.</creatorcontrib><collection>Istex</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of pharmaceutical sciences</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Fayez, M.B.E.</au><au>Negm, S.A.R.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Mass Spectrometric Behavior of Cardiac Steroid Aglycones of the Cardenolide Type</atitle><jtitle>Journal of pharmaceutical sciences</jtitle><addtitle>J. Pharm. Sci</addtitle><date>1972-05</date><risdate>1972</risdate><volume>61</volume><issue>5</issue><spage>765</spage><epage>769</epage><pages>765-769</pages><issn>0022-3549</issn><eissn>1520-6017</eissn><abstract>The mass spectra of several cardenolide aglycones are discussed, and the principal modes of fragmentation are outlined. In addition to conventional expulsions of functional groups, the spectra exhibit C15, C16, and C17 fragment ions, resulting by elimination of ring D and the side chain as well as ions comprising the latter group with remnants of ring D.</abstract><cop>Washington</cop><pub>Elsevier Inc</pub><pmid>5035786</pmid><doi>10.1002/jps.2600610519</doi><tpages>5</tpages></addata></record>
fulltext	fulltext
identifier	ISSN: 0022-3549
ispartof	Journal of pharmaceutical sciences, 1972-05, Vol.61 (5), p.765-769
issn	0022-3549 1520-6017
language	eng
recordid	cdi_proquest_miscellaneous_81486593
source	MEDLINE; Wiley Online Library Journals Frontfile Complete; Alma/SFX Local Collection
subjects	Cardanolides cardenolides Cardenolides-analysis Cardenolides—analysis, mass spectroscopy Cardiac steroid aglycones Cardiac steroid aglycones, cardenolides—analysis, mass spectroscopy Chemical Phenomena Chemistry Mass Spectrometry mass spectroscopy Mass spectroscopy-analysis Mass spectroscopy—analysis, cardenolides Structure-Activity Relationship
title	Mass Spectrometric Behavior of Cardiac Steroid Aglycones of the Cardenolide Type
url	https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-16T15%3A48%3A50IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Mass%20Spectrometric%20Behavior%20of%20Cardiac%20Steroid%20Aglycones%20of%20the%20Cardenolide%20Type&rft.jtitle=Journal%20of%20pharmaceutical%20sciences&rft.au=Fayez,%20M.B.E.&rft.date=1972-05&rft.volume=61&rft.issue=5&rft.spage=765&rft.epage=769&rft.pages=765-769&rft.issn=0022-3549&rft.eissn=1520-6017&rft_id=info:doi/10.1002/jps.2600610519&rft_dat=%3Cproquest_cross%3E81486593%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=81486593&rft_id=info:pmid/5035786&rft_els_id=S0022354915384586&rfr_iscdi=true