Glycolysis: A re-evaluation of the effect on blood glucose

Glycolysis causes considerable errors in blood glucose measurements if some preservative is not included in the blood collection tube. Errors up to 24% can be expected in a routine laboratory if serum is substituted for preserved plasma as the specimen for analysis. Several inorganic fluorides are i...

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Veröffentlicht in:Clinica chimica acta 1972-06, Vol.39 (1), p.35-40
Hauptverfasser: Overfield, C.Verne, Savory, John, Heintges, M.Geraldine
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creator Overfield, C.Verne
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Heintges, M.Geraldine
description Glycolysis causes considerable errors in blood glucose measurements if some preservative is not included in the blood collection tube. Errors up to 24% can be expected in a routine laboratory if serum is substituted for preserved plasma as the specimen for analysis. Several inorganic fluorides are inhibitors of glycolysis, and the two which appear to be most compatible with present day laboratory automation systems are sodium fluoride and ammonium fluoride.
doi_str_mv 10.1016/0009-8981(72)90296-3
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source MEDLINE; Elsevier ScienceDirect Journals
subjects Autoanalysis
Blood Glucose - analysis
Fluorides - pharmacology
Glycolysis - drug effects
Humans
Methods
Quaternary Ammonium Compounds - pharmacology
Sodium - pharmacology
title Glycolysis: A re-evaluation of the effect on blood glucose
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