Glycolysis: A re-evaluation of the effect on blood glucose
Glycolysis causes considerable errors in blood glucose measurements if some preservative is not included in the blood collection tube. Errors up to 24% can be expected in a routine laboratory if serum is substituted for preserved plasma as the specimen for analysis. Several inorganic fluorides are i...
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Veröffentlicht in: | Clinica chimica acta 1972-06, Vol.39 (1), p.35-40 |
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creator | Overfield, C.Verne Savory, John Heintges, M.Geraldine |
description | Glycolysis causes considerable errors in blood glucose measurements if some preservative is not included in the blood collection tube. Errors up to 24% can be expected in a routine laboratory if serum is substituted for preserved plasma as the specimen for analysis.
Several inorganic fluorides are inhibitors of glycolysis, and the two which appear to be most compatible with present day laboratory automation systems are sodium fluoride and ammonium fluoride. |
doi_str_mv | 10.1016/0009-8981(72)90296-3 |
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Several inorganic fluorides are inhibitors of glycolysis, and the two which appear to be most compatible with present day laboratory automation systems are sodium fluoride and ammonium fluoride.</description><identifier>ISSN: 0009-8981</identifier><identifier>EISSN: 1873-3492</identifier><identifier>DOI: 10.1016/0009-8981(72)90296-3</identifier><identifier>PMID: 5038762</identifier><language>eng</language><publisher>Netherlands: Elsevier B.V</publisher><subject>Autoanalysis ; Blood Glucose - analysis ; Fluorides - pharmacology ; Glycolysis - drug effects ; Humans ; Methods ; Quaternary Ammonium Compounds - pharmacology ; Sodium - pharmacology</subject><ispartof>Clinica chimica acta, 1972-06, Vol.39 (1), p.35-40</ispartof><rights>1972</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c357t-10c434961d60598eb3b55e0f83c37b18fe236cf6da8dea3ef582a96c48cb0dcc3</citedby><cites>FETCH-LOGICAL-c357t-10c434961d60598eb3b55e0f83c37b18fe236cf6da8dea3ef582a96c48cb0dcc3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/0009898172902963$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,776,780,3536,27903,27904,65309</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/5038762$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Overfield, C.Verne</creatorcontrib><creatorcontrib>Savory, John</creatorcontrib><creatorcontrib>Heintges, M.Geraldine</creatorcontrib><title>Glycolysis: A re-evaluation of the effect on blood glucose</title><title>Clinica chimica acta</title><addtitle>Clin Chim Acta</addtitle><description>Glycolysis causes considerable errors in blood glucose measurements if some preservative is not included in the blood collection tube. Errors up to 24% can be expected in a routine laboratory if serum is substituted for preserved plasma as the specimen for analysis.
Several inorganic fluorides are inhibitors of glycolysis, and the two which appear to be most compatible with present day laboratory automation systems are sodium fluoride and ammonium fluoride.</description><subject>Autoanalysis</subject><subject>Blood Glucose - analysis</subject><subject>Fluorides - pharmacology</subject><subject>Glycolysis - drug effects</subject><subject>Humans</subject><subject>Methods</subject><subject>Quaternary Ammonium Compounds - pharmacology</subject><subject>Sodium - pharmacology</subject><issn>0009-8981</issn><issn>1873-3492</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1972</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kE1LAzEQhoMotVb_gcKeRA-r-djNZj0IpWgVCl70HLLJRCNpo8luof_e1BaPnoaZ952vB6Fzgm8IJvwWY9yWohXkqqHXLaYtL9kBGhPRsJJVLT1E4z_LMTpJ6TOnFeZkhEY1ZqLhdIzu5n6jg98kl-6KaRGhhLXyg-pdWBXBFv0HFGAt6L7Ihc6HYIp3P-iQ4BQdWeUTnO3jBL09PrzOnsrFy_x5Nl2UmtVNXxKsq3wOJ4bjuhXQsa6uAVvBNGs6IixQxrXlRgkDioGtBVUt15XQHTZaswm63M39iuF7gNTLpUsavFcrCEOSglSC17TKxmpn1DGkFMHKr-iWKm4kwXKLTG55yC0P2VD5i0yy3Haxnz90SzB_TXtGWb_f6ZCfXDuIMmkHKw3GxcxFmuD-X_AD9V56AQ</recordid><startdate>197206</startdate><enddate>197206</enddate><creator>Overfield, C.Verne</creator><creator>Savory, John</creator><creator>Heintges, M.Geraldine</creator><general>Elsevier B.V</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>197206</creationdate><title>Glycolysis: A re-evaluation of the effect on blood glucose</title><author>Overfield, C.Verne ; Savory, John ; Heintges, M.Geraldine</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c357t-10c434961d60598eb3b55e0f83c37b18fe236cf6da8dea3ef582a96c48cb0dcc3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1972</creationdate><topic>Autoanalysis</topic><topic>Blood Glucose - analysis</topic><topic>Fluorides - pharmacology</topic><topic>Glycolysis - drug effects</topic><topic>Humans</topic><topic>Methods</topic><topic>Quaternary Ammonium Compounds - pharmacology</topic><topic>Sodium - pharmacology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Overfield, C.Verne</creatorcontrib><creatorcontrib>Savory, John</creatorcontrib><creatorcontrib>Heintges, M.Geraldine</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Clinica chimica acta</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Overfield, C.Verne</au><au>Savory, John</au><au>Heintges, M.Geraldine</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Glycolysis: A re-evaluation of the effect on blood glucose</atitle><jtitle>Clinica chimica acta</jtitle><addtitle>Clin Chim Acta</addtitle><date>1972-06</date><risdate>1972</risdate><volume>39</volume><issue>1</issue><spage>35</spage><epage>40</epage><pages>35-40</pages><issn>0009-8981</issn><eissn>1873-3492</eissn><abstract>Glycolysis causes considerable errors in blood glucose measurements if some preservative is not included in the blood collection tube. Errors up to 24% can be expected in a routine laboratory if serum is substituted for preserved plasma as the specimen for analysis.
Several inorganic fluorides are inhibitors of glycolysis, and the two which appear to be most compatible with present day laboratory automation systems are sodium fluoride and ammonium fluoride.</abstract><cop>Netherlands</cop><pub>Elsevier B.V</pub><pmid>5038762</pmid><doi>10.1016/0009-8981(72)90296-3</doi><tpages>6</tpages></addata></record> |
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source | MEDLINE; Elsevier ScienceDirect Journals |
subjects | Autoanalysis Blood Glucose - analysis Fluorides - pharmacology Glycolysis - drug effects Humans Methods Quaternary Ammonium Compounds - pharmacology Sodium - pharmacology |
title | Glycolysis: A re-evaluation of the effect on blood glucose |
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