Elevated antithyroid peroxidase antibodies indicating Hashimoto's thyroiditis are associated with the treatment response in infertile women with polycystic ovary syndrome
In infertile women suffering from polycystic ovary syndrome (PCOS), anti-thyroid peroxidase antibodies values exceeding the upper level of normal were found in significantly more clomiphene citrate resistant patients compared clomiphene citrate responders and metformin responders. Thus, elevated ant...
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| Veröffentlicht in: | Fertility and sterility 2010-12, Vol.94 (7), p.2895-2897 |
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| creator | Ott, Johannes, M.D Aust, Stefanie, M.D Kurz, Christine, M.D Nouri, Kazem, M.D Wirth, Stefan, M.D Huber, Johannes C., M.D., Ph.D Mayerhofer, Klaus, M.D |
| description | In infertile women suffering from polycystic ovary syndrome (PCOS), anti-thyroid peroxidase antibodies values exceeding the upper level of normal were found in significantly more clomiphene citrate resistant patients compared clomiphene citrate responders and metformin responders. Thus, elevated antiTPO levels are associated with poor treatment response in infertile women who suffer from PCOS. |
| doi_str_mv | 10.1016/j.fertnstert.2010.05.063 |
| format | Article |
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Thus, elevated antiTPO levels are associated with poor treatment response in infertile women who suffer from PCOS.</description><identifier>ISSN: 0015-0282</identifier><identifier>EISSN: 1556-5653</identifier><identifier>DOI: 10.1016/j.fertnstert.2010.05.063</identifier><identifier>PMID: 20638057</identifier><identifier>CODEN: FESTAS</identifier><language>eng</language><publisher>New York, NY: Elsevier Inc</publisher><subject>Adult ; antithyroid peroxidase antibodies ; Autoantibodies - analysis ; Autoantibodies - blood ; Autoantigens - immunology ; Autoimmune thyroiditis ; Biological and medical sciences ; Biomarkers, Pharmacological - blood ; Clomiphene - therapeutic use ; clomiphene citrate resistance ; Drug Resistance - immunology ; Endocrinopathies ; Female ; Female genital diseases ; Fertility Agents, Female - therapeutic use ; Fertilization in Vitro - methods ; Gynecology. Andrology. Obstetrics ; Hashimoto Disease - blood ; Hashimoto Disease - complications ; Hashimoto Disease - diagnosis ; Hashimoto Disease - immunology ; Hashimoto's thyroiditis ; Humans ; Infertility, Female - blood ; Infertility, Female - complications ; Infertility, Female - diagnosis ; Infertility, Female - drug therapy ; Internal Medicine ; Iodide Peroxidase - immunology ; Iron-Binding Proteins - immunology ; Medical sciences ; Non tumoral diseases ; Non tumoral diseases. Target tissue resistance. Benign neoplasms ; Obstetrics and Gynecology ; Ovulation Induction - methods ; polycystic ovary syndrome ; Polycystic Ovary Syndrome - blood ; Polycystic Ovary Syndrome - complications ; Polycystic Ovary Syndrome - immunology ; Pregnancy ; Prognosis ; Retrospective Studies ; Thyroid. 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Thus, elevated antiTPO levels are associated with poor treatment response in infertile women who suffer from PCOS.</description><subject>Adult</subject><subject>antithyroid peroxidase antibodies</subject><subject>Autoantibodies - analysis</subject><subject>Autoantibodies - blood</subject><subject>Autoantigens - immunology</subject><subject>Autoimmune thyroiditis</subject><subject>Biological and medical sciences</subject><subject>Biomarkers, Pharmacological - blood</subject><subject>Clomiphene - therapeutic use</subject><subject>clomiphene citrate resistance</subject><subject>Drug Resistance - immunology</subject><subject>Endocrinopathies</subject><subject>Female</subject><subject>Female genital diseases</subject><subject>Fertility Agents, Female - therapeutic use</subject><subject>Fertilization in Vitro - methods</subject><subject>Gynecology. Andrology. Obstetrics</subject><subject>Hashimoto Disease - blood</subject><subject>Hashimoto Disease - complications</subject><subject>Hashimoto Disease - diagnosis</subject><subject>Hashimoto Disease - immunology</subject><subject>Hashimoto's thyroiditis</subject><subject>Humans</subject><subject>Infertility, Female - blood</subject><subject>Infertility, Female - complications</subject><subject>Infertility, Female - diagnosis</subject><subject>Infertility, Female - drug therapy</subject><subject>Internal Medicine</subject><subject>Iodide Peroxidase - immunology</subject><subject>Iron-Binding Proteins - immunology</subject><subject>Medical sciences</subject><subject>Non tumoral diseases</subject><subject>Non tumoral diseases. Target tissue resistance. Benign neoplasms</subject><subject>Obstetrics and Gynecology</subject><subject>Ovulation Induction - methods</subject><subject>polycystic ovary syndrome</subject><subject>Polycystic Ovary Syndrome - blood</subject><subject>Polycystic Ovary Syndrome - complications</subject><subject>Polycystic Ovary Syndrome - immunology</subject><subject>Pregnancy</subject><subject>Prognosis</subject><subject>Retrospective Studies</subject><subject>Thyroid. 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Andrology. Obstetrics</topic><topic>Hashimoto Disease - blood</topic><topic>Hashimoto Disease - complications</topic><topic>Hashimoto Disease - diagnosis</topic><topic>Hashimoto Disease - immunology</topic><topic>Hashimoto's thyroiditis</topic><topic>Humans</topic><topic>Infertility, Female - blood</topic><topic>Infertility, Female - complications</topic><topic>Infertility, Female - diagnosis</topic><topic>Infertility, Female - drug therapy</topic><topic>Internal Medicine</topic><topic>Iodide Peroxidase - immunology</topic><topic>Iron-Binding Proteins - immunology</topic><topic>Medical sciences</topic><topic>Non tumoral diseases</topic><topic>Non tumoral diseases. Target tissue resistance. Benign neoplasms</topic><topic>Obstetrics and Gynecology</topic><topic>Ovulation Induction - methods</topic><topic>polycystic ovary syndrome</topic><topic>Polycystic Ovary Syndrome - blood</topic><topic>Polycystic Ovary Syndrome - complications</topic><topic>Polycystic Ovary Syndrome - immunology</topic><topic>Pregnancy</topic><topic>Prognosis</topic><topic>Retrospective Studies</topic><topic>Thyroid. Thyroid axis (diseases)</topic><topic>Young Adult</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Ott, Johannes, M.D</creatorcontrib><creatorcontrib>Aust, Stefanie, M.D</creatorcontrib><creatorcontrib>Kurz, Christine, M.D</creatorcontrib><creatorcontrib>Nouri, Kazem, M.D</creatorcontrib><creatorcontrib>Wirth, Stefan, M.D</creatorcontrib><creatorcontrib>Huber, Johannes C., M.D., Ph.D</creatorcontrib><creatorcontrib>Mayerhofer, Klaus, M.D</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Fertility and sterility</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Ott, Johannes, M.D</au><au>Aust, Stefanie, M.D</au><au>Kurz, Christine, M.D</au><au>Nouri, Kazem, M.D</au><au>Wirth, Stefan, M.D</au><au>Huber, Johannes C., M.D., Ph.D</au><au>Mayerhofer, Klaus, M.D</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Elevated antithyroid peroxidase antibodies indicating Hashimoto's thyroiditis are associated with the treatment response in infertile women with polycystic ovary syndrome</atitle><jtitle>Fertility and sterility</jtitle><addtitle>Fertil Steril</addtitle><date>2010-12-01</date><risdate>2010</risdate><volume>94</volume><issue>7</issue><spage>2895</spage><epage>2897</epage><pages>2895-2897</pages><issn>0015-0282</issn><eissn>1556-5653</eissn><coden>FESTAS</coden><abstract>In infertile women suffering from polycystic ovary syndrome (PCOS), anti-thyroid peroxidase antibodies values exceeding the upper level of normal were found in significantly more clomiphene citrate resistant patients compared clomiphene citrate responders and metformin responders. 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| ispartof | Fertility and sterility, 2010-12, Vol.94 (7), p.2895-2897 |
| issn | 0015-0282 1556-5653 |
| language | eng |
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| source | MEDLINE; Access via ScienceDirect (Elsevier); EZB-FREE-00999 freely available EZB journals; Alma/SFX Local Collection |
| subjects | Adult antithyroid peroxidase antibodies Autoantibodies - analysis Autoantibodies - blood Autoantigens - immunology Autoimmune thyroiditis Biological and medical sciences Biomarkers, Pharmacological - blood Clomiphene - therapeutic use clomiphene citrate resistance Drug Resistance - immunology Endocrinopathies Female Female genital diseases Fertility Agents, Female - therapeutic use Fertilization in Vitro - methods Gynecology. Andrology. Obstetrics Hashimoto Disease - blood Hashimoto Disease - complications Hashimoto Disease - diagnosis Hashimoto Disease - immunology Hashimoto's thyroiditis Humans Infertility, Female - blood Infertility, Female - complications Infertility, Female - diagnosis Infertility, Female - drug therapy Internal Medicine Iodide Peroxidase - immunology Iron-Binding Proteins - immunology Medical sciences Non tumoral diseases Non tumoral diseases. Target tissue resistance. Benign neoplasms Obstetrics and Gynecology Ovulation Induction - methods polycystic ovary syndrome Polycystic Ovary Syndrome - blood Polycystic Ovary Syndrome - complications Polycystic Ovary Syndrome - immunology Pregnancy Prognosis Retrospective Studies Thyroid. Thyroid axis (diseases) Young Adult |
| title | Elevated antithyroid peroxidase antibodies indicating Hashimoto's thyroiditis are associated with the treatment response in infertile women with polycystic ovary syndrome |
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