Studies of a methionine-activating enzyme

Studies of a methionine-activating enzyme

The properties of a methionine-activating enzyme in human erythrocytes and those of other species are described. Several compounds were examined for their capacity to inhibit the enzyme. Electrophoretic mobility of the enzyme from human and animal tissues was investigated by starch block electrophor...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Biochemical pharmacology 1972-03, Vol.21 (6), p.803-809
Hauptverfasser: Cohn, Cal K., Vesell, Elliot S., Axelrod, Julius
Format: Artikel
Sprache:eng
Schlagworte:
Adenosine Triphosphate
Amino Acids - pharmacology
Animals
Carbamates - pharmacology
Cats
Chromatography, Paper
Cyclopentanes - pharmacology
Dogs
Electrophoresis, Starch Gel
Erythrocytes - enzymology
Ethionine - pharmacology
Female
Guinea Pigs
Haplorhini
Humans
Hydrogen-Ion Concentration
Male
Methionine - pharmacology
Methods
Mice
Organ Specificity
Rabbits
Rats
S-Adenosylmethionine - biosynthesis
Transferases - antagonists & inhibitors
Transferases - blood
Tritium
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:The properties of a methionine-activating enzyme in human erythrocytes and those of other species are described. Several compounds were examined for their capacity to inhibit the enzyme. Electrophoretic mobility of the enzyme from human and animal tissues was investigated by starch block electrophoresis. Possible clinical applications of this new assay are discussed.
ISSN:0006-2952
1873-2968
DOI:10.1016/0006-2952(72)90123-2