The occurrence of IgM and complement factors along myelin sheaths of peripheral nerves An immunohistochemical study of the Guillain-Barré syndrome: Preliminary communication

The occurrence of IgM and complement factors along myelin sheaths of peripheral nerves An immunohistochemical study of the Guillain-Barré syndrome: Preliminary communication

In nerve biopsies from 4 of 6 patients with the Guillain-Barré syndrome (GBS), IgM and complement factors were found, probably localized along myelin sheaths. The possible significance of this phenomenon has been discussed. No such findings were obtained in control subjects.

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Bibliographische Detailangaben
Veröffentlicht in:Journal of the neurological sciences 1972-01, Vol.15 (2), p.219-224
Hauptverfasser: Luijten, J.A.F.M., De La Faille-Kuyper, E.H.Baart
Format: Artikel
Sprache:eng
Schlagworte:
Adolescent
Adult
Aged
Antibodies
Complement System Proteins
Demyelinating Diseases - immunology
Fluorescent Antibody Technique
Humans
Immune Sera
Immunoelectrophoresis
Immunoglobulin M
Middle Aged
Myelin Sheath - immunology
Peripheral Nerves - immunology
Peripheral Nervous System Diseases - immunology
Polyradiculopathy - immunology
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Beschreibung
Zusammenfassung:In nerve biopsies from 4 of 6 patients with the Guillain-Barré syndrome (GBS), IgM and complement factors were found, probably localized along myelin sheaths. The possible significance of this phenomenon has been discussed. No such findings were obtained in control subjects.
ISSN:0022-510X
1878-5883
DOI:10.1016/0022-510X(72)90009-3