Messenger RNA Structure: Compatibility of Hairpin Loops with Protein Sequence

Examination of the amino acid sequences of human cytochrome c and the α-chain variant of human hemoglobin Constant Spring has revealed the possibility for base-paired hairpin loops in the messenger RNA's for these proteins. A similar analysis of the bacteriophage R17 coat protein suggests an ad...

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Veröffentlicht in:	Science (American Association for the Advancement of Science) 1972-03, Vol.175 (4027), p.1264-1266
Hauptverfasser:	White, Harold B., Laux, Brian E., Dennis, Don
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Amino acids Bacteriophages - analysis Base Sequence Capsid proteins Computer programming Cytochromes Cytochromes - analysis Genetic Code Hemoglobins Hemoglobins, Abnormal - analysis Humans Iodides Messenger RNA Nucleic Acid Conformation Nucleotide sequences Nucleotides - analysis RNA RNA, Messenger - analysis Urine
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creator	White, Harold B. Laux, Brian E. Dennis, Don
description	Examination of the amino acid sequences of human cytochrome c and the α-chain variant of human hemoglobin Constant Spring has revealed the possibility for base-paired hairpin loops in the messenger RNA's for these proteins. A similar analysis of the bacteriophage R17 coat protein suggests an additional unobserved loop in the R17 RNA. If such loops are present in messenger RNA's generally, it would suggest that DNA has more than one stable base-paired conformation.
doi_str_mv	10.1126/science.175.4027.1264
format	Article
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source	American Association for the Advancement of Science; Jstor Complete Legacy; MEDLINE
subjects	Amino Acid Sequence Amino acids Bacteriophages - analysis Base Sequence Capsid proteins Computer programming Cytochromes Cytochromes - analysis Genetic Code Hemoglobins Hemoglobins, Abnormal - analysis Humans Iodides Messenger RNA Nucleic Acid Conformation Nucleotide sequences Nucleotides - analysis RNA RNA, Messenger - analysis Urine
title	Messenger RNA Structure: Compatibility of Hairpin Loops with Protein Sequence
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