The C-reactive protein determination as a measure of rheumatic activity

1. 1. C-reactive protein determinations were performed on the sera of twenty-four rheumatic fever patients in order to help determine the presence or absence of activity. 2. 2. There was a close correlation between the inactive state and a negative C-reactive protein determination. However, there were two instances of a negative C-reactive protein in the presence of rheumatic activity. 3. 3. A positive test in Sydenham's chorea should suggest the presence of an associated carditis. 4. 4. The C-reactive protein determination was a better guide to activity than the sedimentation rate which showed protracted elevation despite the inactive state.