Possible Biochemical Model for Phenylketonuria

SINCE the demonstration of the primary enzymatic defect in phenylketonuria (PKU) several models have been suggested for this metabolic disorder. No hypothesis, however, has unified the biochemical and clinical characteristics 2 .

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Bibliographische Detailangaben
Veröffentlicht in:	Nature (London) 1972-01, Vol.235 (5335), p.230-230
Hauptverfasser:	BOWDEN, JOE A, MCARTHUR, C. L
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Brain - metabolism Humanities and Social Sciences Humans letter Liver - metabolism Models, Biological multidisciplinary Phenylalanine - metabolism Phenylketonurias - etiology Phenylketonurias - metabolism Phenylpyruvic Acids - metabolism Phenylpyruvic Acids - pharmacology Pyruvates - antagonists & inhibitors Rats Science Science (multidisciplinary) Tissue Extracts - metabolism
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Beschreibung
Zusammenfassung:	SINCE the demonstration of the primary enzymatic defect in phenylketonuria (PKU) several models have been suggested for this metabolic disorder. No hypothesis, however, has unified the biochemical and clinical characteristics 2 .
ISSN:	0028-0836 1476-4687
DOI:	10.1038/235230a0