Effects of extracellular calcium and magnesium on junctional intercellular communication in human fibroblasts

The role of extracellular calcium and magnesium in intercellular communication via permeable junctions was studied by measuring metabolic co-operation between ASS − and ASL − human fibroblasts. Communication through pre-existing junctions was not affected by the removal of extracellular calcium and...

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Veröffentlicht in:	Experimental cell research 1984-01, Vol.155 (2), p.406-412
Hauptverfasser:	Davidson, J.S., Baumgarten, I.M., Harley, E.H.
Format:	Artikel
Sprache:	eng
Schlagworte:	calcium Calcium - pharmacology Cell Communication - drug effects cell junctions Cell Line fibroblasts Fibroblasts - cytology Humans Intercellular Junctions - drug effects Intercellular Junctions - physiology Intercellular Junctions - ultrastructure Kinetics magnesium Magnesium - pharmacology man Skin - cytology
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Beschreibung
Zusammenfassung:	The role of extracellular calcium and magnesium in intercellular communication via permeable junctions was studied by measuring metabolic co-operation between ASS − and ASL − human fibroblasts. Communication through pre-existing junctions was not affected by the removal of extracellular calcium and magnesium from the medium. On the other hand, the establishment of communication through new permeable junctions, when ASS − and ASL − cells were mixed, was dependent on the presence of extracellular calcium and magnesium.
ISSN:	0014-4827 1090-2422
DOI:	10.1016/0014-4827(84)90201-5