Mass spectrometry of glycoproteins: O-glycosyl derivatives of L-serine and L-threonine

Mass spectrometry of glycoproteins: O-glycosyl derivatives of L-serine and L-threonine

The mass spectra of acetylated O-glycosyl derivatives of serine and threonine methyl esters show characteristic features which allow identification of the amino acid and sugar moieties and the type of linkage between them. Some information concerning the sequence of sugar units and the position of t...

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Veröffentlicht in:Carbohydrate research 1971-12, Vol.20 (2), p.275-283
Hauptverfasser: Chizhov, O.S., derevitskaya, V.A., Zolotarev, B.M., Likhosherstov, L.M., Novikova, O.S., Kochetkov, N.K.
Format: Artikel
Sprache:eng
Schlagworte:
Amino Sugars - analysis
Esters - analysis
Glycoproteins - analysis
Mass Spectrometry
Serine - analysis
Spectrum Analysis
Stereoisomerism
Threonine - analysis
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Zusammenfassung:The mass spectra of acetylated O-glycosyl derivatives of serine and threonine methyl esters show characteristic features which allow identification of the amino acid and sugar moieties and the type of linkage between them. Some information concerning the sequence of sugar units and the position of the glycosidic bond in the carbohydrate moiety of disaccharide O-glycosyl derivatives of serine methyl ester is provided also by mass spectrometry.
ISSN:0008-6215
1873-426X
DOI:10.1016/S0008-6215(00)81381-6