Enzyme markers in inbred rat strains: genetics of new markers and strain profiles

Twenty-six inbred strains of the laboratory rat (Rattus norvegicus) were examined for electrophoretic variation at an estimated 97 genetic loci. In addition to previously documented markers, variation was observed for the enzymes aconitase, aldehyde dehydrogenase, and alkaline phosphatase. The genet...

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Veröffentlicht in:	Biochemical genetics 1984-08, Vol.22 (7-8), p.611-629
Hauptverfasser:	ADAMS, M, BAVERSTOCK, P. R, WATTS, C. H. S, GUTMAN, G. A
Format:	Artikel
Sprache:	eng
Schlagworte:	Aconitate Hydratase - genetics Aldehyde Dehydrogenase - genetics Alkaline Phosphatase - genetics Alleles Animals Biological and medical sciences Classical genetics, quantitative genetics, hybrids Enzymes - genetics Female Fundamental and applied biological sciences. Psychology Genetic Linkage Genetic Variation Genetics of eukaryotes. Biological and molecular evolution Male Polymorphism, Genetic Rats Rats, Inbred Strains - genetics Species Specificity Vertebrata
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Zusammenfassung:	Twenty-six inbred strains of the laboratory rat (Rattus norvegicus) were examined for electrophoretic variation at an estimated 97 genetic loci. In addition to previously documented markers, variation was observed for the enzymes aconitase, aldehyde dehydrogenase, and alkaline phosphatase. The genetic basis of these markers (Acon-1, Ahd-2, and Akp-1) was confirmed. Linkage analysis between 35 pairwise comparisons revealed that the markers Fh-1 and Pep-3 are linked. The strain profiles of the 25 inbred strains at 11 electrophoretic markers are given.
ISSN:	0006-2928 1573-4927
DOI:	10.1007/BF00485848