Sertoli-Leydig Cell Tumor of the Ovary Producing α-Fetoprotein

SUMMARYA 16-year-old girl with virilization and elevated serum α-fetoprotein (AFP) levels was found to have a Sertoli-Leydig cell tumor of the ovary. Immunoperoxidase studies using anti-AFP localized AFP in cells with the histologic appearance of Leydig cells. Serum AFP fell to undetectable levels a...

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Veröffentlicht in:	International journal of gynecological pathology 1984-01, Vol.3 (2), p.213-219
Hauptverfasser:	Chumas, J C, Rosenwaks, Z, Mann, W J, Finkel, G, Pastore, J
Format:	Artikel
Sprache:	eng
Schlagworte:	Acne Vulgaris - etiology Adolescent alpha-Fetoproteins - metabolism Amenorrhea - etiology Biological and medical sciences Female Female genital diseases Gynecology. Andrology. Obstetrics Humans Immunoenzyme Techniques Leydig Cell Tumor - complications Leydig Cell Tumor - metabolism Leydig Cell Tumor - pathology Medical sciences Ovarian Neoplasms - complications Ovarian Neoplasms - metabolism Ovarian Neoplasms - pathology Ovary - pathology Sertoli Cell Tumor - complications Sertoli Cell Tumor - metabolism Sertoli Cell Tumor - pathology Tumors Virilism - etiology
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Zusammenfassung:	SUMMARYA 16-year-old girl with virilization and elevated serum α-fetoprotein (AFP) levels was found to have a Sertoli-Leydig cell tumor of the ovary. Immunoperoxidase studies using anti-AFP localized AFP in cells with the histologic appearance of Leydig cells. Serum AFP fell to undetectable levels after excision of the tumor. The patient is alive and well 1 year postexcision.
ISSN:	0277-1691 1538-7151
DOI:	10.1097/00004347-198402000-00009