Effect of polycations and polyanions on cell division of cultured mammalian cells

Effect of polycations and polyanions on cell division of cultured mammalian cells

The polycations (H1 histone and polylysine) and polyanions (heparin and various RNA preparations) stimulate cell division of cultured mammalian cells. The mechanism by which both polycations (H1 histone and polylysine) and polyanions (heparin and RNA) may increase the rate of cell division are discu...

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Veröffentlicht in:Life sciences (1973) 1984-08, Vol.35 (8), p.911-916
Hauptverfasser: Richman, R., Flickinger, R.A.
Format: Artikel
Sprache:eng
Schlagworte:
Animals
Cell Division - drug effects
Cells, Cultured
Heparin - pharmacology
Histones - pharmacology
Leukemia, Erythroblastic, Acute - pathology
Mice
Molecular Weight
Peptides - pharmacology
Poly dA-dT - pharmacology
Poly I-C - pharmacology
Polylysine - pharmacology
RNA - pharmacology
RNA, Ribosomal - pharmacology
RNA, Transfer - pharmacology
Time Factors
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Zusammenfassung:The polycations (H1 histone and polylysine) and polyanions (heparin and various RNA preparations) stimulate cell division of cultured mammalian cells. The mechanism by which both polycations (H1 histone and polylysine) and polyanions (heparin and RNA) may increase the rate of cell division are discussed.
ISSN:0024-3205
1879-0631
DOI:10.1016/0024-3205(84)90418-1