Left ventricular function in chronic anemia: Evidence of noncatecholamine positive inotropic factor in the serum

The enhanced left ventricular (LV) performance observed in anemia has been attributed to changes in preload and afterload. Whether there is a concomitant increase in contractility is controversial. Seventeen patients with chronic anemia (hematocrit range 17 to 30%) and 17 control subjects, matched b...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	The American journal of cardiology 1984-09, Vol.54 (6), p.638-645
Hauptverfasser:	Florenzano, Fernando, Diaz, Gabriela, Regonesi, Carlos, Escobar, Edgardo
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Anemia - blood Anemia - physiopathology Animals Blood Pressure Cats Echocardiography Epinephrine - blood Heart - physiopathology Heart Ventricles - physiopathology Humans In Vitro Techniques Myocardial Contraction Norepinephrine - blood Papillary Muscles - drug effects Papillary Muscles - physiopathology Propranolol - pharmacology Stroke Volume
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	The enhanced left ventricular (LV) performance observed in anemia has been attributed to changes in preload and afterload. Whether there is a concomitant increase in contractility is controversial. Seventeen patients with chronic anemia (hematocrit range 17 to 30%) and 17 control subjects, matched by age and sex, were studied. In 10 patients and 10 control subjects (group I), a noninvasive evaluation of LV function through M-mode echocardiography and cuff blood pressure recording was performed. In patients with anemia, stroke volume increased 43% (p < 0.01), fractional shortening 21% (p
ISSN:	0002-9149 1879-1913
DOI:	10.1016/0002-9149(84)90264-9