A review of the antigens of Fasciola hepatica

The interaction between the antigens of Fasciola hepatica and the host immune response are reviewed. This paper evaluates not only more recent work, but the older literature as well. Antigens from each stage in the life cycle are considered with the idea of identifying those antigens with a potentia...

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Veröffentlicht in:Veterinary parasitology 1984-01, Vol.14 (3), p.209-229
Hauptverfasser: Reddington, John J., Wes Leid, R., Wescott, R.B.
Format: Artikel
Sprache:eng
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Zusammenfassung:The interaction between the antigens of Fasciola hepatica and the host immune response are reviewed. This paper evaluates not only more recent work, but the older literature as well. Antigens from each stage in the life cycle are considered with the idea of identifying those antigens with a potential for use in an effective vaccine. Antigens which cross-react with other parasite species are detailed as well as those that cross-react between different stages in the life cycle of F. hepatica. The objective of the review is to demonstrate for other investigators that vaccination against F. hepatica is a distinct possibility. We hope to encourage more investigators to initiate work on this aspect of an economically-important cosmopolitan parasite.
ISSN:0304-4017
1873-2550
DOI:10.1016/0304-4017(84)90092-X