Effect of Vehicle Dielectric Properties on Rectal Absorption of Acetaminophen

The rectal absorption of acetaminophen from an aqueous suspension, a propylene glycol suspension, and a theobroma oil suppository was measured by urinary excretion. The results are discussed in terms of their relationship to the dielectric constants of the vehicles.

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Veröffentlicht in:Journal of pharmaceutical sciences 1971-04, Vol.60 (4), p.600-602
Hauptverfasser: Shangraw, Ralph F., Douglas Walkling, W.
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container_title Journal of pharmaceutical sciences
container_volume 60
creator Shangraw, Ralph F.
Douglas Walkling, W.
description The rectal absorption of acetaminophen from an aqueous suspension, a propylene glycol suspension, and a theobroma oil suppository was measured by urinary excretion. The results are discussed in terms of their relationship to the dielectric constants of the vehicles.
doi_str_mv 10.1002/jps.2600600419
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identifier ISSN: 0022-3549
ispartof Journal of pharmaceutical sciences, 1971-04, Vol.60 (4), p.600-602
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1520-6017
language eng
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source MEDLINE; Wiley Online Library All Journals; Alma/SFX Local Collection
subjects Absorption
Acetaminophen - metabolism
Acetaminophen - urine
acetaminophen-effect of vehicle dielectric constant
Acetaminophen-rectal absorption from aqueous suspension
Acetaminophen—rectal absorption from aqueous suspension, propylene glycol suspension, theobroma oil suppository, relationship to dielectric constants
Adult
Biological Transport
Chemical Phenomena
Chemistry
Dielectric constant-role in rectal absorption of acetaminophen in different vehicles
Humans
Male
Pharmaceutical Vehicles
propylene glycol suspension
Propylene Glycols
Rectal absorption
Rectal absorption, acetaminophen—effect of vehicle dielectric constant
Rectum
relationship to dielectric constants
Solubility
Suppositories - analysis
theobroma oil suppository
Time Factors
title Effect of Vehicle Dielectric Properties on Rectal Absorption of Acetaminophen
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