Neutralization by an antibody of some vascular actions of bradykinin
Rabbits injected with bradykinin coupled to either ovalbumen or human gamma globulin produced antibodies which are able to neutralize the actions of bradykinin on the isolated perfused vein from the rabbit ear and on the autoperfused dog hind limb. This suggests an application for these antibodies i...
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Veröffentlicht in: | Biochemical pharmacology 1971-11, Vol.20 (11), p.3179-3184 |
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creator | Martin, C.A. Mashford, M.L. Roberts, M.L. |
description | Rabbits injected with bradykinin coupled to either ovalbumen or human gamma globulin produced antibodies which are able to neutralize the actions of bradykinin on the isolated perfused vein from the rabbit ear and on the autoperfused dog hind limb. This suggests an application for these antibodies in the investigation of kinin function. |
doi_str_mv | 10.1016/0006-2952(71)90122-5 |
format | Article |
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This suggests an application for these antibodies in the investigation of kinin function.</description><identifier>ISSN: 0006-2952</identifier><identifier>EISSN: 1873-2968</identifier><identifier>DOI: 10.1016/0006-2952(71)90122-5</identifier><identifier>PMID: 4108901</identifier><language>eng</language><publisher>England: Elsevier Inc</publisher><subject>Animals ; Antibodies, Anti-Idiotypic ; Antibody Formation - drug effects ; Antigen-Antibody Reactions ; Bradykinin - pharmacology ; Dogs ; Femoral Artery ; gamma-Globulins ; Immune Sera ; Ovalbumin ; Protein Binding ; Rabbits ; Regional Blood Flow - drug effects</subject><ispartof>Biochemical pharmacology, 1971-11, Vol.20 (11), p.3179-3184</ispartof><rights>1971</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c357t-c64b45dc927ffd1a7529b70476fbe1bf39c3825ff439dbd184d1cd5f9beec5c73</citedby><cites>FETCH-LOGICAL-c357t-c64b45dc927ffd1a7529b70476fbe1bf39c3825ff439dbd184d1cd5f9beec5c73</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/0006-2952(71)90122-5$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,780,784,3550,27924,27925,45995</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/4108901$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Martin, C.A.</creatorcontrib><creatorcontrib>Mashford, M.L.</creatorcontrib><creatorcontrib>Roberts, M.L.</creatorcontrib><title>Neutralization by an antibody of some vascular actions of bradykinin</title><title>Biochemical pharmacology</title><addtitle>Biochem Pharmacol</addtitle><description>Rabbits injected with bradykinin coupled to either ovalbumen or human gamma globulin produced antibodies which are able to neutralize the actions of bradykinin on the isolated perfused vein from the rabbit ear and on the autoperfused dog hind limb. This suggests an application for these antibodies in the investigation of kinin function.</description><subject>Animals</subject><subject>Antibodies, Anti-Idiotypic</subject><subject>Antibody Formation - drug effects</subject><subject>Antigen-Antibody Reactions</subject><subject>Bradykinin - pharmacology</subject><subject>Dogs</subject><subject>Femoral Artery</subject><subject>gamma-Globulins</subject><subject>Immune Sera</subject><subject>Ovalbumin</subject><subject>Protein Binding</subject><subject>Rabbits</subject><subject>Regional Blood Flow - drug effects</subject><issn>0006-2952</issn><issn>1873-2968</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1971</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kMtKxDAUhoMo4zj6BgpdiS6qOWnTtBtBxisMutF1yBWibaNJO1Cf3tYZZikEQs5_OeRD6BTwFWAorjHGRUoqSi4YXFYYCEnpHppDybJxXJT7aL6zHKKjGD-mZ1nADM1ywOUYmaO7F9N3QdTuR3TOt4kcEtGOp3PS6yHxNom-MclaRNXXIiRCTbY4CTIIPXy61rXH6MCKOpqT7b1A7w_3b8undPX6-Ly8XaUqo6xLVZHLnGpVEWatBsEoqSTDOSusNCBtVqmsJNTaPKu01FDmGpSmtpLGKKpYtkDnm96v4L97EzveuKhMXYvW-D7yEghQwHQ05hujCj7GYCz_Cq4RYeCA-QSPTyj4RIYz4H_w-BQ72_b3sjF6F9rSGvWbjW7GT66dCTwqZ1pltAtGdVx79_-CXxnvfq8</recordid><startdate>197111</startdate><enddate>197111</enddate><creator>Martin, C.A.</creator><creator>Mashford, M.L.</creator><creator>Roberts, M.L.</creator><general>Elsevier Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>197111</creationdate><title>Neutralization by an antibody of some vascular actions of bradykinin</title><author>Martin, C.A. ; Mashford, M.L. ; Roberts, M.L.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c357t-c64b45dc927ffd1a7529b70476fbe1bf39c3825ff439dbd184d1cd5f9beec5c73</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1971</creationdate><topic>Animals</topic><topic>Antibodies, Anti-Idiotypic</topic><topic>Antibody Formation - drug effects</topic><topic>Antigen-Antibody Reactions</topic><topic>Bradykinin - pharmacology</topic><topic>Dogs</topic><topic>Femoral Artery</topic><topic>gamma-Globulins</topic><topic>Immune Sera</topic><topic>Ovalbumin</topic><topic>Protein Binding</topic><topic>Rabbits</topic><topic>Regional Blood Flow - drug effects</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Martin, C.A.</creatorcontrib><creatorcontrib>Mashford, M.L.</creatorcontrib><creatorcontrib>Roberts, M.L.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Biochemical pharmacology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Martin, C.A.</au><au>Mashford, M.L.</au><au>Roberts, M.L.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Neutralization by an antibody of some vascular actions of bradykinin</atitle><jtitle>Biochemical pharmacology</jtitle><addtitle>Biochem Pharmacol</addtitle><date>1971-11</date><risdate>1971</risdate><volume>20</volume><issue>11</issue><spage>3179</spage><epage>3184</epage><pages>3179-3184</pages><issn>0006-2952</issn><eissn>1873-2968</eissn><abstract>Rabbits injected with bradykinin coupled to either ovalbumen or human gamma globulin produced antibodies which are able to neutralize the actions of bradykinin on the isolated perfused vein from the rabbit ear and on the autoperfused dog hind limb. This suggests an application for these antibodies in the investigation of kinin function.</abstract><cop>England</cop><pub>Elsevier Inc</pub><pmid>4108901</pmid><doi>10.1016/0006-2952(71)90122-5</doi><tpages>6</tpages></addata></record> |
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source | MEDLINE; ScienceDirect Journals (5 years ago - present) |
subjects | Animals Antibodies, Anti-Idiotypic Antibody Formation - drug effects Antigen-Antibody Reactions Bradykinin - pharmacology Dogs Femoral Artery gamma-Globulins Immune Sera Ovalbumin Protein Binding Rabbits Regional Blood Flow - drug effects |
title | Neutralization by an antibody of some vascular actions of bradykinin |
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