Neutralization by an antibody of some vascular actions of bradykinin

Rabbits injected with bradykinin coupled to either ovalbumen or human gamma globulin produced antibodies which are able to neutralize the actions of bradykinin on the isolated perfused vein from the rabbit ear and on the autoperfused dog hind limb. This suggests an application for these antibodies i...

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Veröffentlicht in:Biochemical pharmacology 1971-11, Vol.20 (11), p.3179-3184
Hauptverfasser: Martin, C.A., Mashford, M.L., Roberts, M.L.
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container_end_page 3184
container_issue 11
container_start_page 3179
container_title Biochemical pharmacology
container_volume 20
creator Martin, C.A.
Mashford, M.L.
Roberts, M.L.
description Rabbits injected with bradykinin coupled to either ovalbumen or human gamma globulin produced antibodies which are able to neutralize the actions of bradykinin on the isolated perfused vein from the rabbit ear and on the autoperfused dog hind limb. This suggests an application for these antibodies in the investigation of kinin function.
doi_str_mv 10.1016/0006-2952(71)90122-5
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ispartof Biochemical pharmacology, 1971-11, Vol.20 (11), p.3179-3184
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source MEDLINE; ScienceDirect Journals (5 years ago - present)
subjects Animals
Antibodies, Anti-Idiotypic
Antibody Formation - drug effects
Antigen-Antibody Reactions
Bradykinin - pharmacology
Dogs
Femoral Artery
gamma-Globulins
Immune Sera
Ovalbumin
Protein Binding
Rabbits
Regional Blood Flow - drug effects
title Neutralization by an antibody of some vascular actions of bradykinin
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