Neutralization by an antibody of some vascular actions of bradykinin

Rabbits injected with bradykinin coupled to either ovalbumen or human gamma globulin produced antibodies which are able to neutralize the actions of bradykinin on the isolated perfused vein from the rabbit ear and on the autoperfused dog hind limb. This suggests an application for these antibodies i...

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Veröffentlicht in:	Biochemical pharmacology 1971-11, Vol.20 (11), p.3179-3184
Hauptverfasser:	Martin, C.A., Mashford, M.L., Roberts, M.L.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antibodies, Anti-Idiotypic Antibody Formation - drug effects Antigen-Antibody Reactions Bradykinin - pharmacology Dogs Femoral Artery gamma-Globulins Immune Sera Ovalbumin Protein Binding Rabbits Regional Blood Flow - drug effects
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Beschreibung
Zusammenfassung:	Rabbits injected with bradykinin coupled to either ovalbumen or human gamma globulin produced antibodies which are able to neutralize the actions of bradykinin on the isolated perfused vein from the rabbit ear and on the autoperfused dog hind limb. This suggests an application for these antibodies in the investigation of kinin function.
ISSN:	0006-2952 1873-2968
DOI:	10.1016/0006-2952(71)90122-5