Bone Marrow-Derived Cells Contribute to Vascular Inflammation but Do Not Differentiate Into Smooth Muscle Cell Lineages

It has been proposed that bone marrow-derived cells infiltrate the neointima, where they differentiate into smooth muscle (SM) cells; however, technical limitations have hindered clear identification of the lineages of bone marrow-derived "SM cell-like" cells. Using a specific antibody aga...

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Veröffentlicht in:	Circulation (New York, N.Y.) N.Y.), 2010-11, Vol.122 (20), p.2048-2057
Hauptverfasser:	IWATA, Hiroshi, MANABE, Ichiro, FUJIU, Katsuhito, YAMAMOTO, Tetsufumi, TAKEDA, Norifumi, EGUCHI, Kosei, FURUYA, Akiko, KURO-O, Makoto, SATA, Masataka, NAGAI, Ryozo
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antigens, Differentiation - genetics Antigens, Differentiation - metabolism Apolipoproteins E - genetics Apolipoproteins E - metabolism Biological and medical sciences Blood and lymphatic vessels Blood vessels and receptors Bone Marrow Cells - metabolism Bone Marrow Cells - pathology Bone Marrow Transplantation Cardiology. Vascular system Cell Differentiation Disease Models, Animal Diseases of the peripheral vessels. Diseases of the vena cava. Miscellaneous Fundamental and applied biological sciences. Psychology Heart Transplantation Humans Inflammation - etiology Inflammation - genetics Inflammation - metabolism Inflammation - pathology Medical sciences Mice Mice, Knockout Muscle, Smooth, Vascular - metabolism Muscle, Smooth, Vascular - pathology Myocytes, Smooth Muscle - metabolism Myocytes, Smooth Muscle - pathology Transplantation, Homologous Vasculitis - etiology Vasculitis - genetics Vasculitis - metabolism Vasculitis - pathology Vertebrates: cardiovascular system
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