Presence of Sarcoma Genome in a “Non-infectious” Mammalian Virus

Virus particles, antigenically related to mouse sarcoma virus, can be induced from hamster tumour cells. They are “defective” in their failure to replicate in or transform hamster, mouse or rat cells, although they contain viral-specific RNA and, with “helper” mouse leukaemia virus, show sarcomageni...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Nature. New biology (London) 1971-11, Vol.234 (46), p.69-72
Hauptverfasser:	GAZDAR, A. F., PHILLIPS, L. A., SARMA, P. S., PEEBLES, P. T., CHOPRA, H. C.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antigens, Neoplasm - analysis Antigens, Viral - analysis Biomedical and Life Sciences Cell Transformation, Neoplastic Cells, Cultured - microbiology Centrifugation, Density Gradient Cricetinae Gammaretrovirus - immunology Gammaretrovirus - isolation & purification Leukemia Virus, Murine Life Sciences Microscopy, Electron Neoplasms, Experimental - microbiology RNA, Viral - analysis Sarcoma, Experimental - microbiology Tritium Uridine - metabolism Virus Replication
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	Virus particles, antigenically related to mouse sarcoma virus, can be induced from hamster tumour cells. They are “defective” in their failure to replicate in or transform hamster, mouse or rat cells, although they contain viral-specific RNA and, with “helper” mouse leukaemia virus, show sarcomagenic activity.
ISSN:	0090-0028 2058-1092
DOI:	10.1038/newbio234069a0