Sputum Changes Associated with the Use of Ipratropium Bromide

Sputum Changes Associated with the Use of Ipratropium Bromide

Long-term effects of ipratropium bromide (IB) were evaluated using a double-blind cross-over design in 23 adult chronic bronchitic participants. Two 20-μg doses of either IB or placebo were administered as an inhalant four times a day for a period of seven weeks. Sputum volume expectorated during a...

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Veröffentlicht in:Chest 1984-09, Vol.86 (3), p.387-393
Hauptverfasser: Ghafouri, Mo A, Patil, Kashinath D., Kass, Irving
Format: Artikel
Sprache:eng
Schlagworte:
Adult
Aged
Atropine Derivatives - therapeutic use
Biological and medical sciences
Bronchitis - drug therapy
Double-Blind Method
Drug Evaluation
Eosinophils - analysis
Female
Humans
Ipratropium - pharmacology
Ipratropium - therapeutic use
Male
Medical sciences
Middle Aged
Neutrophils - analysis
Pharmacology. Drug treatments
Respiratory Function Tests
Respiratory system
Sputum - analysis
Sputum - drug effects
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Zusammenfassung:Long-term effects of ipratropium bromide (IB) were evaluated using a double-blind cross-over design in 23 adult chronic bronchitic participants. Two 20-μg doses of either IB or placebo were administered as an inhalant four times a day for a period of seven weeks. Sputum volume expectorated during a 24-hour period decreased significantly (p
ISSN:0012-3692
1931-3543
DOI:10.1378/chest.86.3.387