Maternal transmission of hepatocellular carcinoma

A family in which four members have died of hepatocellular carcinoma is presented. Hepatitis B surface antigen was present in both cases in which it was sought and also present in nine of ten surviving siblings in the second generation. Maternal transmission of hepatitis B surface antigen and suscep...

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Veröffentlicht in:	Cancer 1984-10, Vol.54 (7), p.1360-1363
Hauptverfasser:	Harvey, Vernon J., Woodfield, D. Graeme, Probert, John C.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Biological and medical sciences Carcinoma, Hepatocellular - genetics Carcinoma, Hepatocellular - immunology European Continental Ancestry Group Female Gastroenterology. Liver. Pancreas. Abdomen Genotype Hepatitis A - immunology Hepatitis B Antibodies - analysis Hepatitis B Antibodies - genetics Humans Liver Neoplasms - genetics Liver Neoplasms - immunology Liver. Biliary tract. Portal circulation. Exocrine pancreas Male Medical sciences Middle Aged New Zealand Pedigree Tumors
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Beschreibung
Zusammenfassung:	A family in which four members have died of hepatocellular carcinoma is presented. Hepatitis B surface antigen was present in both cases in which it was sought and also present in nine of ten surviving siblings in the second generation. Maternal transmission of hepatitis B surface antigen and susceptibility to hepatocellular carcinoma is postulated.
ISSN:	0008-543X 1097-0142
DOI:	10.1002/1097-0142(19841001)54:7<1360::AID-CNCR2820540721>3.0.CO;2-C