The metabolism and placental transfer of oral and parenteral iron chelates

The present studies in rats provide evidence that in pregnancy, as in iron deficiency anemia, the capacity for enhancement of oral iron absorption extends to some chelated forms of the metal. Iron derived from absorbed or parenteral chelate is available to the placenta and fetus. Nitrilotriacetic ac...

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Veröffentlicht in:	Clinica chimica acta 1971-12, Vol.35 (2), p.311-315
Hauptverfasser:	Bagley, D.H., Zapolski, E.J., Rubin, Martin, Princiotto, J.V.
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetates - pharmacology Administration, Oral Animals Embryo, Mammalian - metabolism Female Gestational Age Injections, Intraperitoneal Injections, Intravenous Intestinal Absorption Iron Chelating Agents - administration & dosage Iron Chelating Agents - metabolism Iron Isotopes Maternal-Fetal Exchange Nitriles - pharmacology Pregnancy Rats
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Beschreibung
Zusammenfassung:	The present studies in rats provide evidence that in pregnancy, as in iron deficiency anemia, the capacity for enhancement of oral iron absorption extends to some chelated forms of the metal. Iron derived from absorbed or parenteral chelate is available to the placenta and fetus. Nitrilotriacetic acid (NTA), is an effective oral iron source in pregnancy.
ISSN:	0009-8981 1873-3492
DOI:	10.1016/0009-8981(71)90199-9