Polymorphism of Human Constitutive Heterochromatin

Polymorphism of Human Constitutive Heterochromatin

Genetic polymorphism has been demonstrated in man for many characteristics including blood groups, serum proteins, tissue enzymes, and hemoglobins. A class of chromosomal polymorphism involving constitutive heterochromatin has now been found. Through the use of a special technique that permits visua...

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Veröffentlicht in:Science (American Association for the Advancement of Science) 1971-11, Vol.174 (4010), p.702-704
Hauptverfasser: Craig-Holmes, Ann P., Shaw, Margery W.
Format: Artikel
Sprache:eng
Schlagworte:
Cell nucleus
Chromatin
Chromosome morphology
Chromosomes
Chromosomes, Human, 1-3
Chromosomes, Human, 13-15
Chromosomes, Human, 16-18
Chromosomes, Human, 19-20
Chromosomes, Human, 21-22 and Y
Chromosomes, Human, 6-12 and X
Crossovers
Cultured cells
DNA
Herpesviridae
Heterochromatin
Human herpesvirus 2
Humans
Lymphocytes
Methods
Nucleic Acid Denaturation
Nucleic Acid Renaturation
Polymorphism, Genetic
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Beschreibung
Zusammenfassung:Genetic polymorphism has been demonstrated in man for many characteristics including blood groups, serum proteins, tissue enzymes, and hemoglobins. A class of chromosomal polymorphism involving constitutive heterochromatin has now been found. Through the use of a special technique that permits visualization of heterochromatin, seven heterochromatin variants have been found among four individuals. These results suggest a very high frequency of variability of heterochromatin in the population.
ISSN:0036-8075
1095-9203
DOI:10.1126/science.174.4010.702