Correlation of histopathologic evidence of disease activity with the presence of immunoglobulin-containing cells in the colons of patients with inflammatory bowel disease

Immunofluoresence of formalin-fixed, paraffin-embedded tissues was performed to study the plasma cell population in 114 colonic specimens from 58 patients. Correlation of the histopathologic stage of disease activity with the isotypes and numbers of immunoglobulin-containing cells in the lamina prop...

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Veröffentlicht in:	Human pathology 1984-08, Vol.15 (8), p.757-763
Hauptverfasser:	Keren, D.F., Appelman, H.D., Dobbins, W.O., Wells, J.J., Whisenant, B., Foley, J., Dieterle, R., Geisinger, K.
Format:	Artikel
Sprache:	eng
Schlagworte:	Antigen-Antibody Complex - analysis Biological and medical sciences Biopsy Colitis, Ulcerative - immunology Colitis, Ulcerative - pathology Colon - cytology Colon - immunology Crohn Disease - immunology Crohn Disease - pathology Fluorescent Antibody Technique Gastroenterology. Liver. Pancreas. Abdomen Humans Immunoglobulin A - analysis Immunoglobulin G - analysis Immunoglobulin M - analysis Immunoglobulins - analysis Intestinal Mucosa - immunology Medical sciences Other diseases. Semiology Plasma Cells - immunology Stomach. Duodenum. Small intestine. Colon. Rectum. Anus
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Zusammenfassung:	Immunofluoresence of formalin-fixed, paraffin-embedded tissues was performed to study the plasma cell population in 114 colonic specimens from 58 patients. Correlation of the histopathologic stage of disease activity with the isotypes and numbers of immunoglobulin-containing cells in the lamina propria demonstrated highly significant ( P
ISSN:	0046-8177 1532-8392
DOI:	10.1016/S0046-8177(84)80167-7