Pyloric stenosis: father and two sons

There are multiple references in the literature as to the hereditary nature of pyloric stenosis.1 Many of these are not authenticated due to the lack of surgical and/or autopsy findings. This disease itself is thought to carry an incidence of 3 cases per 1,000 births.2 Carter has done extensive follow-ups on a series of index patients treated operatively from 1920 to 1939. We would like to report a family with the father and first two offspring sons being affected. Case 1 On October 13, 1937 1-month-old L. H. was seen due to the vomiting of all intake since birth. He had lost 1 pound in the week prior to being seen.