AN EVALUATION OF SINGLE-DOSE METRONIDAZOLE TREATMENT FOR GARDNERELLA VAGINALIS VAGINITIS

A randomized, nonblinded study was carried out to evaluate the efficacy of a single 2-g oral dose of metronidazole (Flagyl) versus a seven-day regimen in the treatment of “nonspecific‘’ vaginitis. Using cultures for Gardnerella vaginalis, 14 (67%) of 21 women treated with the single 2-g dose and 19...

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Veröffentlicht in:	Obstetrics and gynecology (New York. 1953) 1984-08, Vol.64 (2), p.271-273
Hauptverfasser:	Purdon, Alfred, Hanna, John H, Morse, Pari L, Paine, Donald D, Engelkirk, Paul G
Format:	Artikel
Sprache:	eng
Schlagworte:	Administration, Oral Antibacterial agents Antibiotics. Antiinfectious agents. Antiparasitic agents Biological and medical sciences Clinical Trials as Topic Female Follow-Up Studies Gardnerella vaginalis - isolation & purification Haemophilus Infections - drug therapy Humans Medical sciences Metronidazole - administration & dosage Patient Compliance Pharmacology. Drug treatments Random Allocation Time Factors Vaginitis - drug therapy Vaginitis - etiology Vaginitis - microbiology
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Zusammenfassung:	A randomized, nonblinded study was carried out to evaluate the efficacy of a single 2-g oral dose of metronidazole (Flagyl) versus a seven-day regimen in the treatment of “nonspecific‘’ vaginitis. Using cultures for Gardnerella vaginalis, 14 (67%) of 21 women treated with the single 2-g dose and 19 (86%) of 21 women receiving the seven-day course were considered cured seven to ten days after treatment (P > .10). No difference in compliance was noted between the two groups, and the incidence of side effects likewise, was comparable.
ISSN:	0029-7844 1873-233X