approach to the antiinflammatory activity of Borjatriol

Abstract The antiinflammatory activity of borjatriol (a diterpenoid isolated from SIDERITIS MUGRONENSIS Borja) was tested using the cotton pellet-granuloma assay. The compound inhibited the granuloma weight and the serum lysozyme activity in a dose-dependently way. The determination of this enzyme h...

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Veröffentlicht in:	Planta medica 1984-02, Vol.50 (1), p.90-92
Hauptverfasser:	Villar, A, Salom, R, Alcaraz, M.J
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Bones, joints and connective tissue. Antiinflammatory agents Medical sciences nonfood plant products Pharmacology. Drug treatments
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Zusammenfassung:	Abstract The antiinflammatory activity of borjatriol (a diterpenoid isolated from SIDERITIS MUGRONENSIS Borja) was tested using the cotton pellet-granuloma assay. The compound inhibited the granuloma weight and the serum lysozyme activity in a dose-dependently way. The determination of this enzyme has allowed us to distinguish between an irritant (carrageenan) which reduces the granuloma weight and antiinflammatory substances (phenylbutazone and borjatriol).
ISSN:	0032-0943 1439-0221
DOI:	10.1055/s-2007-969630