Inhibitors of hydrogen peroxide-induced haemolysis of bovine erythrocytes

The optimal conditions for the haemolysis of bovine erythrocytes by H 2O 2 have been established. The parameters were concentration of erythrocytes, H 2O 2 concentration, time, and influence of the solvent in which the substances tested were dissolved. Some inhibitors of this oxidative haemolysis ha...

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Veröffentlicht in:	Biochemical pharmacology 1984-06, Vol.33 (12), p.1893-1895
Hauptverfasser:	Chandra Jha, Hem, Bergmann, Christiane, Zilliken, Fritz
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetates - pharmacology Animals Biological and medical sciences Blood. Blood coagulation. Reticuloendothelial system Cattle Dose-Response Relationship, Drug Hemolysis - drug effects Hydrogen Peroxide - pharmacology In Vitro Techniques Medical sciences Pharmacology. Drug treatments Phenols - pharmacology Structure-Activity Relationship
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Zusammenfassung:	The optimal conditions for the haemolysis of bovine erythrocytes by H 2O 2 have been established. The parameters were concentration of erythrocytes, H 2O 2 concentration, time, and influence of the solvent in which the substances tested were dissolved. Some inhibitors of this oxidative haemolysis have been employed to serve as model substances for further antihaemolytic investigations with natural products.
ISSN:	0006-2952 1873-2968
DOI:	10.1016/0006-2952(84)90544-6