Antitumor Principles from Ginkgo biloba L

Seven long-chain phenols were isolated from Ginkgo biloba L. Three of them, anacardic acid (Ib), bilobol (IIa), and cardanol (IIIa), showed antitumor activity against Sarcoma 180 ascites in mice. The antitumor effectiveness was rated (+ +) for Ib, (+ + +) for IIa, and (+ + +) for IIIa at 40 mg/kg/d...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Chemical & pharmaceutical bulletin 1987/07/25, Vol.35(7), pp.3016-3020
Hauptverfasser:	ITOKAWA, HIDER, TOTSUKA, NOBUO, NAKAHARA, KEISUKE, TAKEYA, KOICHI, LEPOITTEVIN, JEAN-PIERRE, ASAKAWA, YOSHINORI
Format:	Artikel
Sprache:	eng
Schlagworte:	anacardic acid Animals Antineoplastic Agents, Phytogenic - pharmacology antitumor activity bilobol Biological and medical sciences cardanol General pharmacology Ginkgo biloba Ginkgoaceae Japan Male Medical sciences Mice Mice, Inbred ICR Pharmacognosy. Homeopathy. Health food Pharmacology. Drug treatments Plants, Medicinal - analysis Sarcoma 180 ascites
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	Seven long-chain phenols were isolated from Ginkgo biloba L. Three of them, anacardic acid (Ib), bilobol (IIa), and cardanol (IIIa), showed antitumor activity against Sarcoma 180 ascites in mice. The antitumor effectiveness was rated (+ +) for Ib, (+ + +) for IIa, and (+ + +) for IIIa at 40 mg/kg/d by the total packed cell volume method.
ISSN:	0009-2363 1347-5223
DOI:	10.1248/cpb.35.3016