Vasopressin increases 45Ca2+ influx in rat aortic smooth muscle cells
[Arg8]Vasopressin (AVP)-induced 45Ca2+ influx was examined in vascular smooth muscle cells derived from rat aorta. AVP stimulated the 45Ca2+ influx in a concentration-dependent manner. The effect was abolished in the presence of La3+. The dihydropyridine calcium channel antagonist darodipine did not...
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| Veröffentlicht in: | Biochemical and biophysical research communications 1987-10, Vol.148 (1), p.273-278 |
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| container_title | Biochemical and biophysical research communications |
| container_volume | 148 |
| creator | Wallnöfer, A Cauvin, C Rüegg, U T |
| description | [Arg8]Vasopressin (AVP)-induced 45Ca2+ influx was examined in vascular smooth muscle cells derived from rat aorta. AVP stimulated the 45Ca2+ influx in a concentration-dependent manner. The effect was abolished in the presence of La3+. The dihydropyridine calcium channel antagonist darodipine did not affect the AVP-induced influx of 45Ca2+. These data suggest that AVP stimulates in these cultured aortic smooth muscle cells a receptor-operated channel (ROC) that is permeable to Ca2+. |
| doi_str_mv | 10.1016/0006-291X(87)91106-5 |
| format | Article |
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AVP stimulated the 45Ca2+ influx in a concentration-dependent manner. The effect was abolished in the presence of La3+. The dihydropyridine calcium channel antagonist darodipine did not affect the AVP-induced influx of 45Ca2+. These data suggest that AVP stimulates in these cultured aortic smooth muscle cells a receptor-operated channel (ROC) that is permeable to Ca2+.</description><identifier>ISSN: 0006-291X</identifier><identifier>DOI: 10.1016/0006-291X(87)91106-5</identifier><identifier>PMID: 3675578</identifier><language>eng</language><publisher>United States</publisher><subject>Animals ; Aorta - drug effects ; Aorta - metabolism ; Arginine Vasopressin - pharmacology ; Calcium - metabolism ; Calcium Channel Blockers - pharmacology ; Cells, Cultured ; Kinetics ; Muscle, Smooth, Vascular - drug effects ; Muscle, Smooth, Vascular - metabolism ; Rats ; Rats, Inbred WKY</subject><ispartof>Biochemical and biophysical research communications, 1987-10, Vol.148 (1), p.273-278</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c1498-c4bbf0a7b850af024f50d9209babb8937832563c586ab70ddc1ff8d557e97e273</citedby><cites>FETCH-LOGICAL-c1498-c4bbf0a7b850af024f50d9209babb8937832563c586ab70ddc1ff8d557e97e273</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27922,27923</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/3675578$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Wallnöfer, A</creatorcontrib><creatorcontrib>Cauvin, C</creatorcontrib><creatorcontrib>Rüegg, U T</creatorcontrib><title>Vasopressin increases 45Ca2+ influx in rat aortic smooth muscle cells</title><title>Biochemical and biophysical research communications</title><addtitle>Biochem Biophys Res Commun</addtitle><description>[Arg8]Vasopressin (AVP)-induced 45Ca2+ influx was examined in vascular smooth muscle cells derived from rat aorta. AVP stimulated the 45Ca2+ influx in a concentration-dependent manner. The effect was abolished in the presence of La3+. The dihydropyridine calcium channel antagonist darodipine did not affect the AVP-induced influx of 45Ca2+. These data suggest that AVP stimulates in these cultured aortic smooth muscle cells a receptor-operated channel (ROC) that is permeable to Ca2+.</description><subject>Animals</subject><subject>Aorta - drug effects</subject><subject>Aorta - metabolism</subject><subject>Arginine Vasopressin - pharmacology</subject><subject>Calcium - metabolism</subject><subject>Calcium Channel Blockers - pharmacology</subject><subject>Cells, Cultured</subject><subject>Kinetics</subject><subject>Muscle, Smooth, Vascular - drug effects</subject><subject>Muscle, Smooth, Vascular - metabolism</subject><subject>Rats</subject><subject>Rats, Inbred WKY</subject><issn>0006-291X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1987</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNo9kE9LxDAQxXNQ1nX1Gyj0JIpUJ23SJEdZ1j-w4EXFW0jSBCvtZs20oN_e1l08DfN483jzI-SMwg0FWt0CQJUXir5fSnGlKB03fkDm__IROUb8BKCUVWpGZmUlOBdyTlZvBuM2ecRmkzUbl7xBjxnjS1Ncj0Joh-9xZMn0mYmpb1yGXYz9R9YN6FqfOd-2eEIOg2nRn-7ngrzer16Wj_n6-eFpebfOHWVK5o5ZG8AIKzmYAAULHGpVgLLGWqlKIcuCV6XjsjJWQF07GoKsx6ZeCV-IckEudrnbFL8Gj73uGpwamI2PA2o5fc4lG41sZ3QpIiYf9DY1nUk_moKeiOkJjZ7QaCn0HzHNx7Pzff5gO1__H-1xlb_mp2gq</recordid><startdate>19871014</startdate><enddate>19871014</enddate><creator>Wallnöfer, A</creator><creator>Cauvin, C</creator><creator>Rüegg, U T</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>19871014</creationdate><title>Vasopressin increases 45Ca2+ influx in rat aortic smooth muscle cells</title><author>Wallnöfer, A ; Cauvin, C ; Rüegg, U T</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c1498-c4bbf0a7b850af024f50d9209babb8937832563c586ab70ddc1ff8d557e97e273</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1987</creationdate><topic>Animals</topic><topic>Aorta - drug effects</topic><topic>Aorta - metabolism</topic><topic>Arginine Vasopressin - pharmacology</topic><topic>Calcium - metabolism</topic><topic>Calcium Channel Blockers - pharmacology</topic><topic>Cells, Cultured</topic><topic>Kinetics</topic><topic>Muscle, Smooth, Vascular - drug effects</topic><topic>Muscle, Smooth, Vascular - metabolism</topic><topic>Rats</topic><topic>Rats, Inbred WKY</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Wallnöfer, A</creatorcontrib><creatorcontrib>Cauvin, C</creatorcontrib><creatorcontrib>Rüegg, U T</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Biochemical and biophysical research communications</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Wallnöfer, A</au><au>Cauvin, C</au><au>Rüegg, U T</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Vasopressin increases 45Ca2+ influx in rat aortic smooth muscle cells</atitle><jtitle>Biochemical and biophysical research communications</jtitle><addtitle>Biochem Biophys Res Commun</addtitle><date>1987-10-14</date><risdate>1987</risdate><volume>148</volume><issue>1</issue><spage>273</spage><epage>278</epage><pages>273-278</pages><issn>0006-291X</issn><abstract>[Arg8]Vasopressin (AVP)-induced 45Ca2+ influx was examined in vascular smooth muscle cells derived from rat aorta. AVP stimulated the 45Ca2+ influx in a concentration-dependent manner. The effect was abolished in the presence of La3+. The dihydropyridine calcium channel antagonist darodipine did not affect the AVP-induced influx of 45Ca2+. These data suggest that AVP stimulates in these cultured aortic smooth muscle cells a receptor-operated channel (ROC) that is permeable to Ca2+.</abstract><cop>United States</cop><pmid>3675578</pmid><doi>10.1016/0006-291X(87)91106-5</doi><tpages>6</tpages></addata></record> |
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| ispartof | Biochemical and biophysical research communications, 1987-10, Vol.148 (1), p.273-278 |
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| language | eng |
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| source | MEDLINE; Elsevier ScienceDirect Journals Complete |
| subjects | Animals Aorta - drug effects Aorta - metabolism Arginine Vasopressin - pharmacology Calcium - metabolism Calcium Channel Blockers - pharmacology Cells, Cultured Kinetics Muscle, Smooth, Vascular - drug effects Muscle, Smooth, Vascular - metabolism Rats Rats, Inbred WKY |
| title | Vasopressin increases 45Ca2+ influx in rat aortic smooth muscle cells |
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