Congenital cataracts in strain 13 guinea pigs: an autosomal dominant human model

Congenital cataracts in strain 13 guinea pigs: an autosomal dominant human model

A spontaneous nuclear cataract seen in strain 13 guinea pigs was inherited under circumstances compatible with it being due to an autosomal dominant gene. This animal model seems advantageous for studies in embryology, developmental neurology, and genetics.

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Bibliographische Detailangaben
Veröffentlicht in:Investigative ophthalmology & visual science 1984-05, Vol.25 (5), p.606-607
Hauptverfasser: Stone, SH, Amsbaugh, DF
Format: Artikel
Sprache:eng
Schlagworte:
Animals
Biological and medical sciences
Cataract - congenital
Cataract - genetics
Genes, Dominant
Guinea Pigs - genetics
Lens diseases
Medical sciences
Models, Biological
Ophthalmology
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Beschreibung
Zusammenfassung:A spontaneous nuclear cataract seen in strain 13 guinea pigs was inherited under circumstances compatible with it being due to an autosomal dominant gene. This animal model seems advantageous for studies in embryology, developmental neurology, and genetics.
ISSN:0146-0404
1552-5783