Relaxation of isolated guinea pig trachea, bronchi and pulmonary arteries produced by vasoactive intestinal peptide (VIP)

Vasoactive intestinal peptide (VIP) relaxed isolated guinea pig airways contracted with carbamylcholine and isolated pulmonary arteries contracted with prostaglandin F 2α. VIP was more potent as a relaxant agonist on trachea than on bronchi but was equipotent on the main and branch pulmonary artery....

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Veröffentlicht in:	European journal of pharmacology 1984-02, Vol.98 (2), p.279-284
Hauptverfasser:	Hand, James M., Laravuso, Raymond B., Will, James A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Air breathing Animals Biological and medical sciences Brochi Bronchi Fundamental and applied biological sciences. Psychology Guinea Pigs In Vitro Techniques Male Muscle Contraction - drug effects Muscle Relaxation - drug effects Muscle, Smooth - physiology Muscle, Smooth, Vascular - physiology Pulmonary Artery Pulmonary smooth muscle Respiratory system: anatomy, metabolism, gas exchange, ventilatory mechanics, respiratory hemodynamics Trachea Vasoactive intestinal peptide Vasoactive Intestinal Peptide - pharmacology Vertebrates: respiratory system
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