Characteristic folding pattern of polytene chromosomes in Drosophila salivary gland nuclei

A computer-based system for recording and analysing light microscope images, combined with classical cytogenetic analysis, has revealed the spatial organization of the giant chromosomes of Drosophila salivary gland cells. Each polytene chromosome arm folds up in a characteristic way, contacts the nu...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Nature (London) 1984-01, Vol.308 (5958), p.414-421
Hauptverfasser:	Mathog, D, Hochstrasser, M, Gruenbaum, Y, Saumweber, H, Sedat, J
Format:	Artikel
Sprache:	eng
Schlagworte:	animal breeding animal genetics Animals arthropods Biological and medical sciences Cell Nucleus - physiology Chromatin. Chromosome Chromosomes - physiology Chromosomes - ultrastructure DNA - genetics Drosophila Drosophila melanogaster - genetics Drosophilidae entomology Fundamental and applied biological sciences. Psychology Humanities and Social Sciences Models, Genetic Models, Molecular Molecular and cellular biology Molecular genetics multidisciplinary Salivary Glands - physiology Science Science (multidisciplinary)
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	A computer-based system for recording and analysing light microscope images, combined with classical cytogenetic analysis, has revealed the spatial organization of the giant chromosomes of Drosophila salivary gland cells. Each polytene chromosome arm folds up in a characteristic way, contacts the nuclear surface at specific sites and is topologically isolated from all other arms.
ISSN:	0028-0836 1476-4687
DOI:	10.1038/308414a0