An experimental study of the influence of antifibrinolytic therapy on post-subarachnoid-hemorrhagic cerebral vasospasm and hydrocephalus

The incidence and severity of cerebral vasospasm and hydrocephalus following induced subarachnoid hemorrhage in an experimental group of animals that subsequently received ε-aminocaproic acid was compared to that seen in a control group that received no antifibrinolytic therapy. No augmentation of e...

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Veröffentlicht in:	Surgical neurology 1984-02, Vol.21 (2), p.159-164
Hauptverfasser:	Kenning, James A., Heros, Roberto C., Dujovny, Manuel, Latchaw, Richard E., Nelson, Debra
Format:	Artikel
Sprache:	eng
Schlagworte:	Aminocaproates - therapeutic use Aminocaproic Acid - therapeutic use Aneurysm Animals Antifibrinolytic therapy Biological and medical sciences Blood. Blood coagulation. Reticuloendothelial system Cerebral Angiography Cerebral Hemorrhage - complications Cerebral Hemorrhage - drug therapy Hydrocephalus Hydrocephalus - complications Hydrocephalus - drug therapy Ischemic Attack, Transient - complications Ischemic Attack, Transient - drug therapy Medical sciences Pharmacology. Drug treatments Recurrence Subarachnoid hemorrhage Subarachnoid Hemorrhage - complications Subarachnoid Hemorrhage - drug therapy Tomography, X-Ray Computed Vasospasm ε-Aminocaproic acid
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Zusammenfassung:	The incidence and severity of cerebral vasospasm and hydrocephalus following induced subarachnoid hemorrhage in an experimental group of animals that subsequently received ε-aminocaproic acid was compared to that seen in a control group that received no antifibrinolytic therapy. No augmentation of either vasospasm or hydrocephalus could be attributed to the ε-aminocaproic acid in the treated as compared to the control group.
ISSN:	0090-3019 1879-3339
DOI:	10.1016/0090-3019(84)90335-5