The Importance of the K1 Capsule in Invasive Infections Caused by Escherichia coli

We examined 534 clinical isolates of Escherichia coli for sensitivity to rough lipopolysaccharide-specific and K1-specific phages. Twenty-eight percent of bacteremic isolates were sensitive to rough-specific phages. Forty-two percent of these strains, against only 20% of bacteremic isolates insensit...

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Veröffentlicht in:	The Journal of infectious diseases 1984-02, Vol.149 (2), p.184-193
Hauptverfasser:	Cross, Alan S., Gemski, Peter, Sadoff, Jerald C., Ørskov, Frits, Ørskov, Ida
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Aged Antigens Antigens, Bacterial - analysis Bacteria Bacterial Capsules Bacteriology Bacteriophage Typing Bacteriophages Biological and medical sciences Blood Blood Bactericidal Activity Capsules Cerebrospinal Fluid - microbiology Child Child, Preschool Electrophoresis, Polyacrylamide Gel Escherichia coli Escherichia coli - classification Escherichia coli Infections - microbiology Feces - microbiology Female Fundamental and applied biological sciences. Psychology Humans Infant Infant, Newborn Infections Lipopolysaccharides - analysis Male Microbiology Middle Aged Molecules O Antigens Pathogenicity, virulence, toxins, bacteriocins, pyrogens, host-bacteria relations, miscellaneous strains Phagocytosis Phenotypes Polysaccharides Polysaccharides, Bacterial - analysis Sepsis - microbiology Serotyping Urinary Tract Infections - microbiology Wounds and Injuries - microbiology
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Zusammenfassung:	We examined 534 clinical isolates of Escherichia coli for sensitivity to rough lipopolysaccharide-specific and K1-specific phages. Twenty-eight percent of bacteremic isolates were sensitive to rough-specific phages. Forty-two percent of these strains, against only 20% of bacteremic isolates insensitive to rough-specific phages, had K1 capsule (P
ISSN:	0022-1899 1537-6613
DOI:	10.1093/infdis/149.2.184